a(MESH:Acetylcholine)

Entity

Name

Acetylcholine

Namespace

mesh

Namespace Version

20180906

Namespace URL

https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/mesh-names.belns

The neurotransmitter acetylcholine (ACh) is synthesised, stored and released by cholinergic neurons, and exerts its effects on the central nervous system (CNS) and peripheral nervous system (PNS) through two distinct types of receptor: the muscarinic and nicotinic ACh receptors (mAChRs and nAChRs). PubMed:28901280

Accordingly, ACh and its synthesizing enzyme choline acetyltransferase (ChAT), are found in human and animal erythrocytes, immune cells, endothelial and epithelial cells (including airway epithelial cells) and placenta cells. Small amounts of ACh are even found in blood PubMed:28901280

Accordingly, ACh and its synthesizing enzyme choline acetyltransferase (ChAT), are found in human and animal erythrocytes, immune cells, endothelial and epithelial cells (including airway epithelial cells) and placenta cells. Small amounts of ACh are even found in blood PubMed:28901280

Airway epithelium cells synthesise, store, process, se- crete and reabsorb ACh, which acts as an autocrine and paracrine growth factor PubMed:28901280

Accordingly, ACh and its synthesizing enzyme choline acetyltransferase (ChAT), are found in human and animal erythrocytes, immune cells, endothelial and epithelial cells (including airway epithelial cells) and placenta cells. Small amounts of ACh are even found in blood PubMed:28901280

but ACh is also released by non-neuronal tissues where it is involved in cell-to-cell communication, and con- trols essential functions such as cell proliferation, adhesion, migration, secretion, survival and apoptosis, in an autocrine, paracrine or juxtacrine manner PubMed:28901280

but ACh is also released by non-neuronal tissues where it is involved in cell-to-cell communication, and con- trols essential functions such as cell proliferation, adhesion, migration, secretion, survival and apoptosis, in an autocrine, paracrine or juxtacrine manner PubMed:28901280

but ACh is also released by non-neuronal tissues where it is involved in cell-to-cell communication, and con- trols essential functions such as cell proliferation, adhesion, migration, secretion, survival and apoptosis, in an autocrine, paracrine or juxtacrine manner PubMed:28901280

but ACh is also released by non-neuronal tissues where it is involved in cell-to-cell communication, and con- trols essential functions such as cell proliferation, adhesion, migration, secretion, survival and apoptosis, in an autocrine, paracrine or juxtacrine manner PubMed:28901280

but ACh is also released by non-neuronal tissues where it is involved in cell-to-cell communication, and con- trols essential functions such as cell proliferation, adhesion, migration, secretion, survival and apoptosis, in an autocrine, paracrine or juxtacrine manner PubMed:28901280

but ACh is also released by non-neuronal tissues where it is involved in cell-to-cell communication, and con- trols essential functions such as cell proliferation, adhesion, migration, secretion, survival and apoptosis, in an autocrine, paracrine or juxtacrine manner PubMed:28901280

but ACh is also released by non-neuronal tissues where it is involved in cell-to-cell communication, and con- trols essential functions such as cell proliferation, adhesion, migration, secretion, survival and apoptosis, in an autocrine, paracrine or juxtacrine manner PubMed:28901280

but ACh is also released by non-neuronal tissues where it is involved in cell-to-cell communication, and con- trols essential functions such as cell proliferation, adhesion, migration, secretion, survival and apoptosis, in an autocrine, paracrine or juxtacrine manner PubMed:28901280

but ACh is also released by non-neuronal tissues where it is involved in cell-to-cell communication, and con- trols essential functions such as cell proliferation, adhesion, migration, secretion, survival and apoptosis, in an autocrine, paracrine or juxtacrine manner PubMed:28901280

but ACh is also released by non-neuronal tissues where it is involved in cell-to-cell communication, and con- trols essential functions such as cell proliferation, adhesion, migration, secretion, survival and apoptosis, in an autocrine, paracrine or juxtacrine manner PubMed:28901280

but ACh is also released by non-neuronal tissues where it is involved in cell-to-cell communication, and con- trols essential functions such as cell proliferation, adhesion, migration, secretion, survival and apoptosis, in an autocrine, paracrine or juxtacrine manner PubMed:28901280

but ACh is also released by non-neuronal tissues where it is involved in cell-to-cell communication, and con- trols essential functions such as cell proliferation, adhesion, migration, secretion, survival and apoptosis, in an autocrine, paracrine or juxtacrine manner PubMed:28901280

but ACh is also released by non-neuronal tissues where it is involved in cell-to-cell communication, and con- trols essential functions such as cell proliferation, adhesion, migration, secretion, survival and apoptosis, in an autocrine, paracrine or juxtacrine manner PubMed:28901280

but ACh is also released by non-neuronal tissues where it is involved in cell-to-cell communication, and con- trols essential functions such as cell proliferation, adhesion, migration, secretion, survival and apoptosis, in an autocrine, paracrine or juxtacrine manner PubMed:28901280

but ACh is also released by non-neuronal tissues where it is involved in cell-to-cell communication, and con- trols essential functions such as cell proliferation, adhesion, migration, secretion, survival and apoptosis, in an autocrine, paracrine or juxtacrine manner PubMed:28901280

but ACh is also released by non-neuronal tissues where it is involved in cell-to-cell communication, and con- trols essential functions such as cell proliferation, adhesion, migration, secretion, survival and apoptosis, in an autocrine, paracrine or juxtacrine manner PubMed:28901280

but ACh is also released by non-neuronal tissues where it is involved in cell-to-cell communication, and con- trols essential functions such as cell proliferation, adhesion, migration, secretion, survival and apoptosis, in an autocrine, paracrine or juxtacrine manner PubMed:28901280

but ACh is also released by non-neuronal tissues where it is involved in cell-to-cell communication, and con- trols essential functions such as cell proliferation, adhesion, migration, secretion, survival and apoptosis, in an autocrine, paracrine or juxtacrine manner PubMed:28901280

but ACh is also released by non-neuronal tissues where it is involved in cell-to-cell communication, and con- trols essential functions such as cell proliferation, adhesion, migration, secretion, survival and apoptosis, in an autocrine, paracrine or juxtacrine manner PubMed:28901280

but ACh is also released by non-neuronal tissues where it is involved in cell-to-cell communication, and con- trols essential functions such as cell proliferation, adhesion, migration, secretion, survival and apoptosis, in an autocrine, paracrine or juxtacrine manner PubMed:28901280

Together with that re- leased by vagal nerve endings, ACh can also contribute to the cholinergic control of inflammation PubMed:28901280

When lung cancer arises from the airway epithelium, cell growth is stimulated by ACh or nicotine, and this growth loop may provide endogenous mitogenic signalling without any further activation PubMed:28901280

α9 and α9-α10 nAChRs have a number of interesting characteristics: they are acti- vated by ACh but not by the classical agonist nicotine. Cho- line is also a potent selective agonist of the α9 subtype PubMed:28901280

α9 and α9-α10 nAChRs have a number of interesting characteristics: they are acti- vated by ACh but not by the classical agonist nicotine. Cho- line is also a potent selective agonist of the α9 subtype PubMed:28901280