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complex(a(MESH:Acetylcholine), p(MESH:"Receptors, Nicotinic"))

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Components

Appears in Networks 1

Neuronal and Extraneuronal Nicotinic Acetylcholine Receptors. v1.0.0

In-Edges 0

Out-Edges 6

complex(a(MESH:Acetylcholine), p(MESH:"Receptors, Nicotinic")) hasComponent a(MESH:Acetylcholine) View Subject | View Object

Appears in Networks:

complex(a(MESH:Acetylcholine), p(MESH:"Receptors, Nicotinic")) hasComponent p(MESH:"Receptors, Nicotinic") View Subject | View Object

Appears in Networks:

complex(a(MESH:Acetylcholine), p(MESH:"Receptors, Nicotinic")) increases act(a(MESH:"Peripheral Nervous System")) View Subject | View Object

The neurotransmitter acetylcholine (ACh) is synthesised, stored and released by cholinergic neurons, and exerts its effects on the central nervous system (CNS) and peripheral nervous system (PNS) through two distinct types of receptor: the muscarinic and nicotinic ACh receptors (mAChRs and nAChRs). PubMed:28901280

Appears in Networks:

complex(a(MESH:Acetylcholine), p(MESH:"Receptors, Nicotinic")) increases tloc(a(MESH:Sodium), fromLoc(GO:"extracellular region"), toLoc(GO:intracellular)) View Subject | View Object

The binding of ACh or nicotine activates neuronal nAChRs thus leading to the influx of Na+ and Ca2+ and ef- flux of K+. PubMed:28901280

Appears in Networks:
Annotations
MeSH
GABAergic Neurons

complex(a(MESH:Acetylcholine), p(MESH:"Receptors, Nicotinic")) increases tloc(a(CHEBI:"calcium cation"), fromLoc(GO:"extracellular region"), toLoc(GO:intracellular)) View Subject | View Object

The binding of ACh or nicotine activates neuronal nAChRs thus leading to the influx of Na+ and Ca2+ and ef- flux of K+. PubMed:28901280

Appears in Networks:
Annotations
MeSH
GABAergic Neurons

complex(a(MESH:Acetylcholine), p(MESH:"Receptors, Nicotinic")) increases tloc(a(CHEBI:"potassium(1+)"), fromLoc(GO:intracellular), toLoc(GO:"extracellular region")) View Subject | View Object

The binding of ACh or nicotine activates neuronal nAChRs thus leading to the influx of Na+ and Ca2+ and ef- flux of K+. PubMed:28901280

Appears in Networks:
Annotations
MeSH
GABAergic Neurons

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.