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a(MESH:"Endothelial Cells")

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Entity

Name
Endothelial Cells
Namespace
MeSH
Namespace Version
20181007
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/01c9daa61012b37dd0a1bc962521ba51a15b38f1/external/mesh-names.belns

Appears in Networks 3

albuquerque2009 v1.0.0

This file encodes the article Mammalian Nicotinic Acetylcholine Receptors: From Structure to Function by Albuquerque et al, 2009

Neuronal and Extraneuronal Nicotinic Acetylcholine Receptors. v1.0.0

Tau clearance mechanisms and their possible role in the pathogenesis of Alzheimer disease v1.0.0

In-Edges 0

Out-Edges 4

a(MESH:"Endothelial Cells") increases p(HGNCGENEFAMILY:"Cholinergic receptors nicotinic subunits") View Subject | View Object

Neuronal nAChRs are not expressed exclusively in neurons. Instead, they are expressed by multiple cell types of diverse origins and functions including glia (165, 167, 425), keratinocytes (44, 86, 95, 426), endothelial cells (290, 495), and multiple cell types of the digestive system, lungs, and immune system (e.g., Refs. 95, 309, 492, 495). PubMed:19126755

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a(MESH:"Endothelial Cells") increases a(MESH:Acetylcholine) View Subject | View Object

Accordingly, ACh and its synthesizing enzyme choline acetyltransferase (ChAT), are found in human and animal erythrocytes, immune cells, endothelial and epithelial cells (including airway epithelial cells) and placenta cells. Small amounts of ACh are even found in blood PubMed:28901280

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a(MESH:"Endothelial Cells") increases a(MESH:"Choline O-Acetyltransferase") View Subject | View Object

Accordingly, ACh and its synthesizing enzyme choline acetyltransferase (ChAT), are found in human and animal erythrocytes, immune cells, endothelial and epithelial cells (including airway epithelial cells) and placenta cells. Small amounts of ACh are even found in blood PubMed:28901280

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a(MESH:"Endothelial Cells") increases sec(a(CHEBI:Thrombin)) View Subject | View Object

Thrombin is a serine protease that is a well characterized component of the coagulation cascade. It is typically produced and secreted by endothelial cells, including those in the brain in response to hemodynamic injury. PubMed:24027553

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MeSH
Brain
Text Location
Review

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.