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path(MESH:"Pulmonary Embolism")

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
Pulmonary Embolism
Namespace
MeSH
Namespace Version
20181007
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/01c9daa61012b37dd0a1bc962521ba51a15b38f1/external/mesh-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 5

a(CHEBI:"L-arginine") negativeCorrelation path(MESH:"Pulmonary Embolism") View Subject | View Object

Humans with severe PE have increased arginase-1 and decreased plasma L-arginine concentrations.[14] PubMed:26337933

Appears in Networks:
Annotations
Text Location
Introduction

a(MESH:Splenectomy) positiveCorrelation path(MESH:"Pulmonary Embolism") View Subject | View Object

The increased risk of thrombosis in patients who undergo a splenectomy is important. About 22 000 splenectomies are still conducted annually for all causes in the United States and splenectomized patients have a 22-fold increased rate of being hospitalized for deep vein thrombosis or pulmonary embolism (Kristinsson et al, 2014). PubMed:25307023

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Plasma
MeSH
Urine
MeSH
beta-Thalassemia
Text Location
Review

p(HGNC:ARG1) positiveCorrelation path(MESH:"Pulmonary Embolism") View Subject | View Object

Humans with severe PE have increased arginase-1 and decreased plasma L-arginine concentrations.[14] PubMed:26337933

Appears in Networks:
Annotations
Text Location
Introduction

path(MESH:"beta-Thalassemia") positiveCorrelation path(MESH:"Pulmonary Embolism") View Subject | View Object

Thrombotic events also occur in b-thalassaemia patients; for example, pulmonary embolism, portal vein thrombosis and deep vein thrombosis occurred in 29% of b-thalassaemia intermedia patients followed for 10 years (Cappellini et al, 2000). PubMed:25307023

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Plasma
MeSH
Urine
MeSH
beta-Thalassemia
Text Location
Review

path(MESH:Hemolysis) positiveCorrelation path(MESH:"Pulmonary Embolism") View Subject | View Object

We hypothesize acute moderate to severe PE causes turbulent flow across the tricuspid and pulmonic valves and in the pulmonary tree, causing rupture of a small percentage of red cells in or immediately proximal to or within the pulmonary vascular tree. PubMed:26337933

Appears in Networks:
Annotations
Cell Ontology (CL)
leukocyte
MeSH
Pulmonary Embolism
Text Location
Discussion

Out-Edges 5

path(MESH:"Pulmonary Embolism") negativeCorrelation a(CHEBI:"L-arginine") View Subject | View Object

Humans with severe PE have increased arginase-1 and decreased plasma L-arginine concentrations.[14] PubMed:26337933

Appears in Networks:
Annotations
Text Location
Introduction

path(MESH:"Pulmonary Embolism") positiveCorrelation path(MESH:"beta-Thalassemia") View Subject | View Object

Thrombotic events also occur in b-thalassaemia patients; for example, pulmonary embolism, portal vein thrombosis and deep vein thrombosis occurred in 29% of b-thalassaemia intermedia patients followed for 10 years (Cappellini et al, 2000). PubMed:25307023

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Plasma
MeSH
Urine
MeSH
beta-Thalassemia
Text Location
Review

path(MESH:"Pulmonary Embolism") positiveCorrelation a(MESH:Splenectomy) View Subject | View Object

The increased risk of thrombosis in patients who undergo a splenectomy is important. About 22 000 splenectomies are still conducted annually for all causes in the United States and splenectomized patients have a 22-fold increased rate of being hospitalized for deep vein thrombosis or pulmonary embolism (Kristinsson et al, 2014). PubMed:25307023

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Plasma
MeSH
Urine
MeSH
beta-Thalassemia
Text Location
Review

path(MESH:"Pulmonary Embolism") positiveCorrelation p(HGNC:ARG1) View Subject | View Object

Humans with severe PE have increased arginase-1 and decreased plasma L-arginine concentrations.[14] PubMed:26337933

Appears in Networks:
Annotations
Text Location
Introduction

path(MESH:"Pulmonary Embolism") positiveCorrelation path(MESH:Hemolysis) View Subject | View Object

We hypothesize acute moderate to severe PE causes turbulent flow across the tricuspid and pulmonic valves and in the pulmonary tree, causing rupture of a small percentage of red cells in or immediately proximal to or within the pulmonary vascular tree. PubMed:26337933

Appears in Networks:
Annotations
Cell Ontology (CL)
leukocyte
MeSH
Pulmonary Embolism
Text Location
Discussion

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.