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Pulmonary Embolism

Name
Pulmonary Embolism
Namespace Keyword
MeSHDisease
Namespace
MeSH
Namespace Version
20170511
Namespace URL
https://arty.scai.fraunhofer.de/artifactory/bel/annotation/mesh-diseases/mesh-diseases-20170511.belanno

Sample Annotated Edges 5

p(HGNC:HBB) positiveCorrelation complex(a(CHEBI:"nitric oxide"), p(HGNC:HBB)) View Subject | View Object

Release of hemoglobin (and ultimately heme), and arginase-1 into the plasma results in binding of nitric oxide and also reduction in L-arginine, respectively, causing a relative reduction in vasodilatory effect.[14,29] PubMed:26337933

Appears in Networks:
Annotations
Cell Ontology (CL)
leukocyte
MeSH
Plasma
MeSH
Pulmonary Embolism
Text Location
Discussion

p(HGNC:HBB) decreases a(CHEBI:"L-arginine") View Subject | View Object

Release of hemoglobin (and ultimately heme), and arginase-1 into the plasma results in binding of nitric oxide and also reduction in L-arginine, respectively, causing a relative reduction in vasodilatory effect.[14,29] PubMed:26337933

Appears in Networks:
Annotations
Cell Ontology (CL)
leukocyte
MeSH
Plasma
MeSH
Pulmonary Embolism
Text Location
Discussion

complex(a(CHEBI:"nitric oxide"), p(HGNC:HBB)) positiveCorrelation p(HGNC:HBB) View Subject | View Object

Release of hemoglobin (and ultimately heme), and arginase-1 into the plasma results in binding of nitric oxide and also reduction in L-arginine, respectively, causing a relative reduction in vasodilatory effect.[14,29] PubMed:26337933

Appears in Networks:
Annotations
Cell Ontology (CL)
leukocyte
MeSH
Plasma
MeSH
Pulmonary Embolism
Text Location
Discussion

p(HGNC:HP) negativeCorrelation path(MESH:"Tricuspid Valve Insufficiency") View Subject | View Object

The median values and associated interquartile ranges for hmox-1 and haptoglobin show that patients with PE+TR+ had lower expression of these genes compared with patients who were PE+TR− or PE− PubMed:26337933

Appears in Networks:
Annotations
MeSH
Pulmonary Embolism
Text Location
Results

p(HGNC:ARG1) positiveCorrelation path(MESH:Hemolysis) View Subject | View Object

Table 3 shows a significant increase in the median value for the plasma biomarker of hemolysis, arginase-1 in patients with PE+TR+ by pairwise comparison using the Kruskal-Wallis test. PubMed:26337933

Appears in Networks:
Annotations
MeSH
Pulmonary Embolism
Text Location
Results

Showing 5 of 16 edges

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.