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a(CHEBI:nitrite)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
nitrite
Namespace
chebi
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/chebi-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 9

a(HM:"stored erythrocytes") negativeCorrelation a(CHEBI:nitrite) View Subject | View Object

We have also shown that older RBCs oxidize nitrite with faster rates compared to younger RBCs, which may account for decreased circulating nitrite levels in trauma patients receiving older RBCs14. PubMed:26202471

Appears in Networks:
Annotations
Text Location
Introduction

a(MESH:Hemodilution) decreases a(CHEBI:nitrite) View Subject | View Object

Thus, we hypothesized that loss of blood during surgery and hemodilution from crystalloid administration might contribute to the observed decrease in plasma NOx levels. PubMed:27308950

Appears in Networks:
Annotations
MeSH
Plasma
Text Location
Results

a(MESH:Hemodilution) decreases a(CHEBI:nitrite) View Subject | View Object

Thus, it was apparent that blood loss and hemodilution from IV fluids rather than stored RBC transfusion likely played a role in the transient decrease of these NO metabolites. PubMed:27308950

Appears in Networks:
Annotations
MeSH
Plasma
Text Location
Discussion

complex(a(CHEBI:"hydrogen peroxide"), a(CHEBI:heme), a(CHEBI:nitrite)) hasComponent a(CHEBI:nitrite) View Subject | View Object

Appears in Networks:

path(MESH:"Blood Loss, Surgical") decreases a(CHEBI:nitrite) View Subject | View Object

Thus, we hypothesized that loss of blood during surgery and hemodilution from crystalloid administration might contribute to the observed decrease in plasma NOx levels. PubMed:27308950

Appears in Networks:
Annotations
MeSH
Plasma
Text Location
Results

path(MESH:"Blood Loss, Surgical") decreases a(CHEBI:nitrite) View Subject | View Object

Thus, it was apparent that blood loss and hemodilution from IV fluids rather than stored RBC transfusion likely played a role in the transient decrease of these NO metabolites. PubMed:27308950

Appears in Networks:
Annotations
MeSH
Plasma
Text Location
Discussion

rxn(reactants(a(CHEBI:deoxyhemoglobin), a(CHEBI:nitrite)), products(a(HM:"heme-NO species"))) hasReactant a(CHEBI:nitrite) View Subject | View Object

Appears in Networks:

rxn(reactants(a(CHEBI:nitrate)), products(a(CHEBI:nitrite))) hasProduct a(CHEBI:nitrite) View Subject | View Object

Appears in Networks:

rxn(reactants(a(CHEBI:nitrite)), products(a(CHEBI:"nitric oxide"))) hasReactant a(CHEBI:nitrite) View Subject | View Object

Appears in Networks:

Out-Edges 1

a(CHEBI:nitrite) negativeCorrelation a(HM:"stored erythrocytes") View Subject | View Object

We have also shown that older RBCs oxidize nitrite with faster rates compared to younger RBCs, which may account for decreased circulating nitrite levels in trauma patients receiving older RBCs14. PubMed:26202471

Appears in Networks:
Annotations
Text Location
Introduction

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.