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rxn(reactants(a(CHEBI:nitrite)), products(a(CHEBI:"nitric oxide")))

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Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 1

a(MESH:Hemeproteins) increases rxn(reactants(a(CHEBI:nitrite)), products(a(CHEBI:"nitric oxide"))) View Subject | View Object

Several studies have shown that nitrite is reduced to NO by several heme proteins under hypoxic conditions, providing an eNOS-independent source of NO in the vasculature.28,47,48. PubMed:27308950

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Annotations
MeSH
Plasma
MeSH
Hypoxia
Text Location
Discussion

Out-Edges 2

rxn(reactants(a(CHEBI:nitrite)), products(a(CHEBI:"nitric oxide"))) hasReactant a(CHEBI:nitrite) View Subject | View Object

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rxn(reactants(a(CHEBI:nitrite)), products(a(CHEBI:"nitric oxide"))) hasProduct a(CHEBI:"nitric oxide") View Subject | View Object

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BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.