a(MESH:Mortality)
However, mortality significantly increased in mice resuscitated with stored RBCs (median survival 8 h, n = 9), with all mice dying within 20 h of PAK instillation (Fig 1C). PubMed:29522519
After resuscitation with SRBCs, only 58% of mice survived for 48 hours (SRBC vs. FRBC, P<0.05). PubMed:27515135
In contrast, all of the mice survived after SRBC-transfusion and treatment with hemopexin (SRBC+Hx vs. SRBC+Alb, P=0.018). Similarly the survival rate of mice resuscitated with SRBCs and co-infusion of haptoglobin was 96% (SRBC+Hp vs. SRBC+Alb, P=0.030). PubMed:27515135
In contrast, all of the mice survived after SRBC-transfusion and treatment with hemopexin (SRBC+Hx vs. SRBC+Alb, P=0.018). Similarly the survival rate of mice resuscitated with SRBCs and co-infusion of haptoglobin was 96% (SRBC+Hp vs. SRBC+Alb, P=0.030). PubMed:27515135
Increased circulating cell-free Hb, heme, and iron and decreased haptoglobin concentrations have been associated with morbidity and mortality in both animal models and patients.4,5 PubMed:29603246
Moderate anemia is associated with increased mortality and morbidity, including acute kidney injury (AKI), in surgical patients. PubMed:29351418
Anemia has been associated with an increased risk of acute kidney injury (AKI) (17, 18, 20, 27, 28), stroke (17, 20, 27), myocardial events (6, 11, 20, 28, 47), and mortality (1, 2, 10, 11, 17, 20, 27, 28, 36, 45, 47) in patients undergoing surgery. PubMed:29351418
After resuscitation with SRBCs, only 58% of mice survived for 48 hours (SRBC vs. FRBC, P<0.05). PubMed:27515135
In contrast, all of the mice survived after SRBC-transfusion and treatment with hemopexin (SRBC+Hx vs. SRBC+Alb, P=0.018). Similarly the survival rate of mice resuscitated with SRBCs and co-infusion of haptoglobin was 96% (SRBC+Hp vs. SRBC+Alb, P=0.030). PubMed:27515135
In contrast, all of the mice survived after SRBC-transfusion and treatment with hemopexin (SRBC+Hx vs. SRBC+Alb, P=0.018). Similarly the survival rate of mice resuscitated with SRBCs and co-infusion of haptoglobin was 96% (SRBC+Hp vs. SRBC+Alb, P=0.030). PubMed:27515135
Moderate anemia is associated with increased mortality and morbidity, including acute kidney injury (AKI), in surgical patients. PubMed:29351418
Anemia has been associated with an increased risk of acute kidney injury (AKI) (17, 18, 20, 27, 28), stroke (17, 20, 27), myocardial events (6, 11, 20, 28, 47), and mortality (1, 2, 10, 11, 17, 20, 27, 28, 36, 45, 47) in patients undergoing surgery. PubMed:29351418
Increased circulating cell-free Hb, heme, and iron and decreased haptoglobin concentrations have been associated with morbidity and mortality in both animal models and patients.4,5 PubMed:29603246
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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.