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p(HGNC:VIM)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
VIM
Namespace
hgnc
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 3

Phosphatase: PP2A structural importance, regulation and its aberrant expression in cancer v1.0.0

Significance of NF-κB as a pivotal therapeutic target in the neurodegenerative pathologies of Alzheimer's disease and multiple sclerosis v1.0.0

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 3

m(HGNC:MIR125B1) positiveCorrelation p(HGNC:VIM) View Subject | View Object

In AD brains, miRNA-125b is observed as the most abundant exhibiting strong positive correlation with glial fibrillary acidic protein and vimentin and negative correlation with reduced cyclin dependent kinase 2A PubMed:25652642

Appears in Networks:
Annotations
MeSH
Brain
MeSH
Alzheimer Disease

a(CHEBI:heme) increases p(HGNC:VIM) View Subject | View Object

In contrast, hemin strongly increased the percentage of neutrophils positive for surface expression of vimentin [mean (SD) 48.8% (20) vs. 2.5% (0.8), n = 5; P , 0.001]. PubMed:28716864

Appears in Networks:
Annotations
Cell Ontology (CL)
endothelial cell
Text Location
Results

p(HGNC:SERPINA1) decreases p(HGNC:VIM) View Subject | View Object

In the presence of A1AT, this latter effect of hemin was significantly inhibited and did not differ from controls (Fig. 5B). PubMed:28716864

Appears in Networks:
Annotations
Cell Ontology (CL)
endothelial cell
Text Location
Results

Out-Edges 2

p(HGNC:VIM) hasVariant p(HGNC:VIM, pmod(Ph)) View Subject | View Object

Appears in Networks:

p(HGNC:VIM) positiveCorrelation m(HGNC:MIR125B1) View Subject | View Object

In AD brains, miRNA-125b is observed as the most abundant exhibiting strong positive correlation with glial fibrillary acidic protein and vimentin and negative correlation with reduced cyclin dependent kinase 2A PubMed:25652642

Appears in Networks:
Annotations
MeSH
Brain
MeSH
Alzheimer Disease

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.