MIR125B1

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Entity

Name: MIR125B1
Namespace: hgnc
Namespace Version: 20190224
Namespace URL: https://raw.githubusercontent.com/pharmacome/terminology/c328ad964c08967a0417a887510b97b965a62fa5/external/hgnc-names.belns

Appears in Networks 1

Significance of NF-κB as a pivotal therapeutic target in the neurodegenerative pathologies of Alzheimer's disease and multiple sclerosis v1.0.0

In-Edges 5

complex(GO:"NF-kappaB complex") regulates m(HGNC:MIR125B1) View Subject | View Object

Upregulation of several NF-κB regulated miRNAs such as miRNA-9, miRNA-34a, miRNA-125b, miRNA-146a, miRNA-155 and miRNA-339 5p have been observed in stressed primary human neuronalglial cells and in postmortem AD brain tissues PubMed:25652642

Appears in Networks:

Significance of NF-κB as a pivotal therapeutic target in the neurodegenerative pathologies of Alzheimer's disease and multiple sclerosis v1.0.0

Annotations

MeSH: Brain
MeSH: Neuroglia
MeSH: Alzheimer Disease

p(HGNC:CDKN2A) positiveCorrelation m(HGNC:MIR125B1) View Subject | View Object

In AD brains, miRNA-125b is observed as the most abundant exhibiting strong positive correlation with glial fibrillary acidic protein and vimentin and negative correlation with reduced cyclin dependent kinase 2A PubMed:25652642

Appears in Networks:

Significance of NF-κB as a pivotal therapeutic target in the neurodegenerative pathologies of Alzheimer's disease and multiple sclerosis v1.0.0

Annotations

MeSH: Brain
MeSH: Alzheimer Disease

p(HGNC:GFAP) positiveCorrelation m(HGNC:MIR125B1) View Subject | View Object

In AD brains, miRNA-125b is observed as the most abundant exhibiting strong positive correlation with glial fibrillary acidic protein and vimentin and negative correlation with reduced cyclin dependent kinase 2A PubMed:25652642

Appears in Networks:

Significance of NF-κB as a pivotal therapeutic target in the neurodegenerative pathologies of Alzheimer's disease and multiple sclerosis v1.0.0

Annotations

MeSH: Brain
MeSH: Alzheimer Disease

p(HGNC:VIM) positiveCorrelation m(HGNC:MIR125B1) View Subject | View Object

In AD brains, miRNA-125b is observed as the most abundant exhibiting strong positive correlation with glial fibrillary acidic protein and vimentin and negative correlation with reduced cyclin dependent kinase 2A PubMed:25652642

Appears in Networks:

Significance of NF-κB as a pivotal therapeutic target in the neurodegenerative pathologies of Alzheimer's disease and multiple sclerosis v1.0.0

Annotations

MeSH: Brain
MeSH: Alzheimer Disease

path(MESH:"Alzheimer Disease") positiveCorrelation m(HGNC:MIR125B1) View Subject | View Object

Upregulation of several NF-κB regulated miRNAs such as miRNA-9, miRNA-34a, miRNA-125b, miRNA-146a, miRNA-155 and miRNA-339 5p have been observed in stressed primary human neuronalglial cells and in postmortem AD brain tissues PubMed:25652642

Appears in Networks:

Significance of NF-κB as a pivotal therapeutic target in the neurodegenerative pathologies of Alzheimer's disease and multiple sclerosis v1.0.0

Annotations

MeSH: Brain
MeSH: Neuroglia
MeSH: Alzheimer Disease

Out-Edges 4

m(HGNC:MIR125B1) positiveCorrelation path(MESH:"Alzheimer Disease") View Subject | View Object

Upregulation of several NF-κB regulated miRNAs such as miRNA-9, miRNA-34a, miRNA-125b, miRNA-146a, miRNA-155 and miRNA-339 5p have been observed in stressed primary human neuronalglial cells and in postmortem AD brain tissues PubMed:25652642

Appears in Networks:

Significance of NF-κB as a pivotal therapeutic target in the neurodegenerative pathologies of Alzheimer's disease and multiple sclerosis v1.0.0

Annotations

MeSH: Brain
MeSH: Neuroglia
MeSH: Alzheimer Disease

m(HGNC:MIR125B1) positiveCorrelation p(HGNC:GFAP) View Subject | View Object

In AD brains, miRNA-125b is observed as the most abundant exhibiting strong positive correlation with glial fibrillary acidic protein and vimentin and negative correlation with reduced cyclin dependent kinase 2A PubMed:25652642

Appears in Networks:

Significance of NF-κB as a pivotal therapeutic target in the neurodegenerative pathologies of Alzheimer's disease and multiple sclerosis v1.0.0

Annotations

MeSH: Brain
MeSH: Alzheimer Disease

m(HGNC:MIR125B1) positiveCorrelation p(HGNC:VIM) View Subject | View Object

In AD brains, miRNA-125b is observed as the most abundant exhibiting strong positive correlation with glial fibrillary acidic protein and vimentin and negative correlation with reduced cyclin dependent kinase 2A PubMed:25652642

Appears in Networks:

Significance of NF-κB as a pivotal therapeutic target in the neurodegenerative pathologies of Alzheimer's disease and multiple sclerosis v1.0.0

Annotations

MeSH: Brain
MeSH: Alzheimer Disease

m(HGNC:MIR125B1) positiveCorrelation p(HGNC:CDKN2A) View Subject | View Object

In AD brains, miRNA-125b is observed as the most abundant exhibiting strong positive correlation with glial fibrillary acidic protein and vimentin and negative correlation with reduced cyclin dependent kinase 2A PubMed:25652642

Appears in Networks:

Significance of NF-κB as a pivotal therapeutic target in the neurodegenerative pathologies of Alzheimer's disease and multiple sclerosis v1.0.0

Annotations

MeSH: Brain
MeSH: Alzheimer Disease

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.