1. Catalog
  2. Nodes
  3. complex(a(CHEBI:"tin atom"), a(CHEBI:protoporphyrin))

complex(a(CHEBI:"tin atom"), a(CHEBI:protoporphyrin))

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Components

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 3

act(p(MGI:Hpx)) negativeCorrelation complex(a(CHEBI:"tin atom"), a(CHEBI:protoporphyrin)) View Subject | View Object

The beneficial effects of Hp and Hpx were lost by inhibition of HO with SnPP, but could be restored by CO administration. PubMed:29694434

Appears in Networks:
Annotations
MeSH
Liver
MeSH
Anemia, Sickle Cell
Text Location
Discussion

act(p(MGI:Hp)) negativeCorrelation complex(a(CHEBI:"tin atom"), a(CHEBI:protoporphyrin)) View Subject | View Object

The beneficial effects of Hp and Hpx were lost by inhibition of HO with SnPP, but could be restored by CO administration. PubMed:29694434

Appears in Networks:
Annotations
MeSH
Liver
MeSH
Anemia, Sickle Cell
Text Location
Discussion

act(p(MGI:Nfkb1)) negativeCorrelation complex(a(CHEBI:"tin atom"), a(CHEBI:protoporphyrin)) View Subject | View Object

SnPP and CO had similar inhibitory effects on NF-kB activation in the liver (data not shown). PubMed:29694434

Appears in Networks:
Annotations
MeSH
Liver
MeSH
Anemia, Sickle Cell
Text Location
Results

Out-Edges 6

complex(a(CHEBI:"tin atom"), a(CHEBI:protoporphyrin)) hasComponent a(CHEBI:"tin atom") View Subject | View Object

Appears in Networks:

complex(a(CHEBI:"tin atom"), a(CHEBI:protoporphyrin)) hasComponent a(CHEBI:protoporphyrin) View Subject | View Object

Appears in Networks:

complex(a(CHEBI:"tin atom"), a(CHEBI:protoporphyrin)) decreases act(p(RGD:Hmox1)) View Subject | View Object

Fig. 4 shows that the inhibition of HO activity by both, SnPP (Fig. 4A) or ZnPP (Fig. 4B), potentiates the effect of heme on VSMC proliferation. PubMed:22954673

Appears in Networks:
Annotations
Cell Ontology (CL)
neutrophil
MeSH
Muscle, Smooth, Vascular
Text Location
Results

complex(a(CHEBI:"tin atom"), a(CHEBI:protoporphyrin)) negativeCorrelation act(p(MGI:Nfkb1)) View Subject | View Object

SnPP and CO had similar inhibitory effects on NF-kB activation in the liver (data not shown). PubMed:29694434

Appears in Networks:
Annotations
MeSH
Liver
MeSH
Anemia, Sickle Cell
Text Location
Results

complex(a(CHEBI:"tin atom"), a(CHEBI:protoporphyrin)) negativeCorrelation act(p(MGI:Hp)) View Subject | View Object

The beneficial effects of Hp and Hpx were lost by inhibition of HO with SnPP, but could be restored by CO administration. PubMed:29694434

Appears in Networks:
Annotations
MeSH
Liver
MeSH
Anemia, Sickle Cell
Text Location
Discussion

complex(a(CHEBI:"tin atom"), a(CHEBI:protoporphyrin)) negativeCorrelation act(p(MGI:Hpx)) View Subject | View Object

The beneficial effects of Hp and Hpx were lost by inhibition of HO with SnPP, but could be restored by CO administration. PubMed:29694434

Appears in Networks:
Annotations
MeSH
Liver
MeSH
Anemia, Sickle Cell
Text Location
Discussion

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.