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  4. Liver

Liver

Name
Liver
Namespace Keyword
MeSHAnatomy
Namespace
MeSH
Namespace Version
20170511
Namespace URL
https://arty.scai.fraunhofer.de/artifactory/bel/annotation/mesh-anatomy/mesh-anatomy-20170511.belanno

Sample Annotated Edges 5

act(a(MESH:"Vagus Nerve")) increases act(p(HGNC:CHRNA7)) View Subject | View Object

Hepatic vagus nerve activity has recently been shown to protect hepatocytes from Fas-induced apoptosis via activation of alpha7 nAChRs (Hiramoto et al., 2008). Thus, nicotine seems to exert a general pro-survival action not only on neurons but also on non-neuronal cells, suggesting that the protection offered by nicotine against Abeta toxicity may therefore simply be the result of a general pro-survival response. PubMed:19293145

Appears in Networks:
Annotations
MeSH
Liver

a(CHEBI:nicotine) association bp(GO:"negative regulation of apoptotic process") View Subject | View Object

Hepatic vagus nerve activity has recently been shown to protect hepatocytes from Fas-induced apoptosis via activation of alpha7 nAChRs (Hiramoto et al., 2008). Thus, nicotine seems to exert a general pro-survival action not only on neurons but also on non-neuronal cells, suggesting that the protection offered by nicotine against Abeta toxicity may therefore simply be the result of a general pro-survival response. PubMed:19293145

Appears in Networks:
Annotations
MeSH
Liver

act(p(HGNC:FAS)) increases bp(GO:"programmed cell death") View Subject | View Object

Hepatic vagus nerve activity has recently been shown to protect hepatocytes from Fas-induced apoptosis via activation of alpha7 nAChRs (Hiramoto et al., 2008). Thus, nicotine seems to exert a general pro-survival action not only on neurons but also on non-neuronal cells, suggesting that the protection offered by nicotine against Abeta toxicity may therefore simply be the result of a general pro-survival response. PubMed:19293145

Appears in Networks:
Annotations
MeSH
Liver

act(p(HGNC:CHRNA7)) decreases act(p(HGNC:FAS)) View Subject | View Object

Hepatic vagus nerve activity has recently been shown to protect hepatocytes from Fas-induced apoptosis via activation of alpha7 nAChRs (Hiramoto et al., 2008). Thus, nicotine seems to exert a general pro-survival action not only on neurons but also on non-neuronal cells, suggesting that the protection offered by nicotine against Abeta toxicity may therefore simply be the result of a general pro-survival response. PubMed:19293145

Appears in Networks:
Annotations
MeSH
Liver

bp(GO:"negative regulation of apoptotic process") association a(CHEBI:nicotine) View Subject | View Object

Hepatic vagus nerve activity has recently been shown to protect hepatocytes from Fas-induced apoptosis via activation of alpha7 nAChRs (Hiramoto et al., 2008). Thus, nicotine seems to exert a general pro-survival action not only on neurons but also on non-neuronal cells, suggesting that the protection offered by nicotine against Abeta toxicity may therefore simply be the result of a general pro-survival response. PubMed:19293145

Appears in Networks:
Annotations
MeSH
Liver

Showing 5 of 371 edges

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.