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path(MESH:"Osteoarthritis, Knee")

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Entity

Name
Osteoarthritis, Knee
Namespace
MeSH
Namespace Version
20181007
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/01c9daa61012b37dd0a1bc962521ba51a15b38f1/external/mesh-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 7

bp(GO:aging) positiveCorrelation path(MESH:"Osteoarthritis, Knee") View Subject | View Object

Obesity, genetic factors, and aging are some of the most prominent risk factors (Sharma et al., 2006), and in the younger population, previous knee injury is an important contributor to increased prevalence of knee OA – as much as half of those sustaining a knee injury in their 20s had developed posttraumatic knee OA in the following 12 to 14 years (Lohmander et al., 2004, 2007; von Porat et al., 2004). PubMed:30505280

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bp(MESH:"Genetic Markers") positiveCorrelation path(MESH:"Osteoarthritis, Knee") View Subject | View Object

Obesity, genetic factors, and aging are some of the most prominent risk factors (Sharma et al., 2006), and in the younger population, previous knee injury is an important contributor to increased prevalence of knee OA – as much as half of those sustaining a knee injury in their 20s had developed posttraumatic knee OA in the following 12 to 14 years (Lohmander et al., 2004, 2007; von Porat et al., 2004). PubMed:30505280

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p(HGNC:AMBP) positiveCorrelation path(MESH:"Osteoarthritis, Knee") View Subject | View Object

In similarity with both studies, we found detectable concentrations of A1M in synovial fluid in subjects with knee OA. PubMed:30505280

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MeSH
Synovial Fluid
MeSH
Osteoarthritis, Knee
Text Location
Discussion

p(HGNC:AMBP) positiveCorrelation path(MESH:"Osteoarthritis, Knee") View Subject | View Object

Finally, we note that in AIA A1M is increased both locally in the joint fluid and systemically in serum, whereas in knee injury A1M is increased only in the joint fluid. PubMed:30505280

Appears in Networks:
Annotations
MeSH
Synovial Fluid
MeSH
Osteoarthritis, Knee
Text Location
Discussion

path(MESH:"Knee Injuries") positiveCorrelation path(MESH:"Osteoarthritis, Knee") View Subject | View Object

Obesity, genetic factors, and aging are some of the most prominent risk factors (Sharma et al., 2006), and in the younger population, previous knee injury is an important contributor to increased prevalence of knee OA – as much as half of those sustaining a knee injury in their 20s had developed posttraumatic knee OA in the following 12 to 14 years (Lohmander et al., 2004, 2007; von Porat et al., 2004). PubMed:30505280

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path(MESH:Obesity) positiveCorrelation path(MESH:"Osteoarthritis, Knee") View Subject | View Object

Obesity, genetic factors, and aging are some of the most prominent risk factors (Sharma et al., 2006), and in the younger population, previous knee injury is an important contributor to increased prevalence of knee OA – as much as half of those sustaining a knee injury in their 20s had developed posttraumatic knee OA in the following 12 to 14 years (Lohmander et al., 2004, 2007; von Porat et al., 2004). PubMed:30505280

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Text Location
Introduction

path(MESH:Pain) positiveCorrelation path(MESH:"Osteoarthritis, Knee") View Subject | View Object

Knee osteoarthritis (OA) is the most common joint disease and is a major cause of pain and disability in the older population worldwide (Liu et al., 2015). PubMed:30505280

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Out-Edges 7

path(MESH:"Osteoarthritis, Knee") positiveCorrelation path(MESH:Pain) View Subject | View Object

Knee osteoarthritis (OA) is the most common joint disease and is a major cause of pain and disability in the older population worldwide (Liu et al., 2015). PubMed:30505280

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Text Location
Introduction

path(MESH:"Osteoarthritis, Knee") positiveCorrelation path(MESH:Obesity) View Subject | View Object

Obesity, genetic factors, and aging are some of the most prominent risk factors (Sharma et al., 2006), and in the younger population, previous knee injury is an important contributor to increased prevalence of knee OA – as much as half of those sustaining a knee injury in their 20s had developed posttraumatic knee OA in the following 12 to 14 years (Lohmander et al., 2004, 2007; von Porat et al., 2004). PubMed:30505280

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Introduction

path(MESH:"Osteoarthritis, Knee") positiveCorrelation bp(GO:aging) View Subject | View Object

Obesity, genetic factors, and aging are some of the most prominent risk factors (Sharma et al., 2006), and in the younger population, previous knee injury is an important contributor to increased prevalence of knee OA – as much as half of those sustaining a knee injury in their 20s had developed posttraumatic knee OA in the following 12 to 14 years (Lohmander et al., 2004, 2007; von Porat et al., 2004). PubMed:30505280

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Text Location
Introduction

path(MESH:"Osteoarthritis, Knee") positiveCorrelation bp(MESH:"Genetic Markers") View Subject | View Object

Obesity, genetic factors, and aging are some of the most prominent risk factors (Sharma et al., 2006), and in the younger population, previous knee injury is an important contributor to increased prevalence of knee OA – as much as half of those sustaining a knee injury in their 20s had developed posttraumatic knee OA in the following 12 to 14 years (Lohmander et al., 2004, 2007; von Porat et al., 2004). PubMed:30505280

Appears in Networks:
Annotations
Text Location
Introduction

path(MESH:"Osteoarthritis, Knee") positiveCorrelation path(MESH:"Knee Injuries") View Subject | View Object

Obesity, genetic factors, and aging are some of the most prominent risk factors (Sharma et al., 2006), and in the younger population, previous knee injury is an important contributor to increased prevalence of knee OA – as much as half of those sustaining a knee injury in their 20s had developed posttraumatic knee OA in the following 12 to 14 years (Lohmander et al., 2004, 2007; von Porat et al., 2004). PubMed:30505280

Appears in Networks:
Annotations
Text Location
Introduction

path(MESH:"Osteoarthritis, Knee") positiveCorrelation p(HGNC:AMBP) View Subject | View Object

In similarity with both studies, we found detectable concentrations of A1M in synovial fluid in subjects with knee OA. PubMed:30505280

Appears in Networks:
Annotations
MeSH
Synovial Fluid
MeSH
Osteoarthritis, Knee
Text Location
Discussion

path(MESH:"Osteoarthritis, Knee") positiveCorrelation p(HGNC:AMBP) View Subject | View Object

Finally, we note that in AIA A1M is increased both locally in the joint fluid and systemically in serum, whereas in knee injury A1M is increased only in the joint fluid. PubMed:30505280

Appears in Networks:
Annotations
MeSH
Synovial Fluid
MeSH
Osteoarthritis, Knee
Text Location
Discussion

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.