Extracellular Traps

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name: Extracellular Traps
Namespace: MeSH
Namespace Version: 20181007
Namespace URL: https://raw.githubusercontent.com/pharmacome/terminology/01c9daa61012b37dd0a1bc962521ba51a15b38f1/external/mesh-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 2

bp(GO:"neutrophil activation") positiveCorrelation a(MESH:"Extracellular Traps") View Subject | View Object

Heme-induced neutrophils activation leads to extracellular traps (NETs) release through a mechanism dependent on ROS generation (Chen et al., 2014). PubMed:24904418

Appears in Networks:

Heme Curation v0.0.1-dev

Annotations

Cell Ontology (CL): erythrocyte
Text Location: Review

path(MESH:Hemolysis) positiveCorrelation a(MESH:"Extracellular Traps") View Subject | View Object

Furthermore, haem released during SCD-induced haemolysis triggers the release of neutrophil extracellular traps (NETs) via a ROS-dependent mechanism (Chen et al, 2014). PubMed:25307023

Appears in Networks:

Heme Curation v0.0.1-dev

Annotations

Cell Ontology (CL): endothelial cell
MeSH: Plasma
MeSH: Urine
MeSH: Anemia, Hemolytic, Autoimmune
Text Location: Review

Out-Edges 4

a(MESH:"Extracellular Traps") positiveCorrelation bp(GO:"neutrophil activation") View Subject | View Object

Heme-induced neutrophils activation leads to extracellular traps (NETs) release through a mechanism dependent on ROS generation (Chen et al., 2014). PubMed:24904418

Appears in Networks:

Heme Curation v0.0.1-dev

Annotations

Cell Ontology (CL): erythrocyte
Text Location: Review

a(MESH:"Extracellular Traps") positiveCorrelation path(MESH:Hemolysis) View Subject | View Object

Furthermore, haem released during SCD-induced haemolysis triggers the release of neutrophil extracellular traps (NETs) via a ROS-dependent mechanism (Chen et al, 2014). PubMed:25307023

Appears in Networks:

Heme Curation v0.0.1-dev

Annotations

Cell Ontology (CL): endothelial cell
MeSH: Plasma
MeSH: Urine
MeSH: Anemia, Hemolytic, Autoimmune
Text Location: Review

a(MESH:"Extracellular Traps") increases bp(MESH:"Platelet Activation") View Subject | View Object

Thus, NETs recruit RBCs, activate platelets and promote fibrin deposition; they are a previously unrecognized link between haemolysis and thrombosis that may further explain this epidemiological association. PubMed:25307023

Appears in Networks:

Heme Curation v0.0.1-dev

Annotations

Cell Ontology (CL): endothelial cell
MeSH: Plasma
MeSH: Urine
MeSH: Anemia, Hemolytic, Autoimmune
Text Location: Review

a(MESH:"Extracellular Traps") increases a(HM:"fibrin deposition") View Subject | View Object

Appears in Networks:

Heme Curation v0.0.1-dev

Annotations

Cell Ontology (CL): endothelial cell
MeSH: Plasma
MeSH: Urine
MeSH: Anemia, Hemolytic, Autoimmune
Text Location: Review

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.