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complex(a(MESH:"Reactive Oxygen Species"), p(HGNC:HBB))

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Components

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 0

Out-Edges 3

complex(a(MESH:"Reactive Oxygen Species"), p(HGNC:HBB)) hasComponent a(MESH:"Reactive Oxygen Species") View Subject | View Object

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complex(a(MESH:"Reactive Oxygen Species"), p(HGNC:HBB)) hasComponent p(HGNC:HBB) View Subject | View Object

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complex(a(MESH:"Reactive Oxygen Species"), p(HGNC:HBB)) increases a(MESH:ferrylhemoglobin) View Subject | View Object

After hemolysis, sustained interaction between Hb and ROS can lead to ferrylhemoglobin (ferrylHb) formation, which is characterized by an increase in the Fe oxidative state to Fe+4 (Harel and Kanner, 1988; Patel et al., 1996). PubMed:24904418

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Annotations
Cell Ontology (CL)
macrophage
MeSH
Liver
MeSH
Cerebral Hemorrhage
Text Location
Review

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.