1. Catalog
  2. Nodes
  3. a(HM:"Platelet margination")

a(HM:"Platelet margination")

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
Platelet margination
Namespace
HM
Namespace Version
None
Pattern
.*

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 2

a(MESH:Erythrocytes) increases a(HM:"Platelet margination") View Subject | View Object

A remarkable rheological effect of RBCs that affects platelets in hemostasis and thrombosis is that RBCs preferentially move down the center of blood vessel, causing margination of platelets, so that they are poised to adhere preferentially to the site of vessel-wall injury [10]. PubMed:28458720

Appears in Networks:
Annotations
Text Location
Review

bp(MESH:"Erythrocyte Deformability") decreases a(HM:"Platelet margination") View Subject | View Object

More rigid RBCs may be less able to squeeze through the capillaries and they also increase platelet margination described above, both of which increase the susceptibility to thrombosis [18]. PubMed:28458720

Appears in Networks:
Annotations
MeSH
Veins
Text Location
Review

Out-Edges 1

a(HM:"Platelet margination") increases path(MESH:Thrombosis) View Subject | View Object

More rigid RBCs may be less able to squeeze through the capillaries and they also increase platelet margination described above, both of which increase the susceptibility to thrombosis [18]. PubMed:28458720

Appears in Networks:
Annotations
MeSH
Veins
Text Location
Review

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.