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p(HGNC:F3)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
F3
Namespace
hgnc
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 4

a(CHEBI:heme) increases p(HGNC:F3) View Subject | View Object

Furthermore, incubating endothelial cells with haem induces tissue factor, which can initiate coagulation (Setty et al, 2008). PubMed:25307023

Appears in Networks:
Annotations
Cell Ontology (CL)
endothelial cell
MeSH
Plasma
MeSH
Urine
MeSH
Anemia, Hemolytic, Autoimmune
Text Location
Review

complex(p(HGNC:F3), p(HGNC:F7)) hasComponent p(HGNC:F3) View Subject | View Object

Appears in Networks:

path(HM:"endothelial lesions") positiveCorrelation p(HGNC:F3) View Subject | View Object

Injured endothelium may provide tissue factors and additional prothrombotic factors [21] that are not a prothrombotic mechanism in PNH. PubMed:29929138

Appears in Networks:
Annotations
Cell Ontology (CL)
platelet
MeSH
Endothelium
MeSH
Hemoglobinuria, Paroxysmal
Text Location
Discussion

path(MESH:"Blood Coagulation") positiveCorrelation p(HGNC:F3) View Subject | View Object

Furthermore, incubating endothelial cells with haem induces tissue factor, which can initiate coagulation (Setty et al, 2008). PubMed:25307023

Appears in Networks:
Annotations
Cell Ontology (CL)
endothelial cell
MeSH
Plasma
MeSH
Urine
MeSH
Anemia, Hemolytic, Autoimmune
Text Location
Review

Out-Edges 3

p(HGNC:F3) positiveCorrelation path(MESH:"Blood Coagulation") View Subject | View Object

Furthermore, incubating endothelial cells with haem induces tissue factor, which can initiate coagulation (Setty et al, 2008). PubMed:25307023

Appears in Networks:
Annotations
Cell Ontology (CL)
endothelial cell
MeSH
Plasma
MeSH
Urine
MeSH
Anemia, Hemolytic, Autoimmune
Text Location
Review

p(HGNC:F3) positiveCorrelation path(HM:"endothelial lesions") View Subject | View Object

Injured endothelium may provide tissue factors and additional prothrombotic factors [21] that are not a prothrombotic mechanism in PNH. PubMed:29929138

Appears in Networks:
Annotations
Cell Ontology (CL)
platelet
MeSH
Endothelium
MeSH
Hemoglobinuria, Paroxysmal
Text Location
Discussion

p(HGNC:F3) increases path(MESH:"Disseminated Intravascular Coagulation") View Subject | View Object

Essential for the development of DIC during sepsis is the so-called pro-coagulatory shift of the endothelial cells, caused among others by an increased expression of tissue factor and adhesion molecules especially by damaged endothelial cells [87]. PubMed:29956069

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Microvessels
MeSH
Sepsis
Text Location
Review

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.