bp(MESH:"Wound Healing")
In addition to the obvious protective benefit of exogenous A1M binding and neutralizing cell-free Hb and heme, it may also be beneficial as a repair mechanism in already damaged cartilage, since in vitro studies showed that collagen fibrils were restored to normal by addition of recombinant A1M after destruction already had begun (Olsson et al., 2011). PubMed:30505280
During the resolution phase of inflammation HO-1 expression in leukocytes reduces adhesion molecules expression and leukocytes migration, thus contributing to wound healing (Wagener et al., 2003a). PubMed:24904418
In addition to the obvious protective benefit of exogenous A1M binding and neutralizing cell-free Hb and heme, it may also be beneficial as a repair mechanism in already damaged cartilage, since in vitro studies showed that collagen fibrils were restored to normal by addition of recombinant A1M after destruction already had begun (Olsson et al., 2011). PubMed:30505280
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