path(MESH:"Plaque, Atherosclerotic")
Gruel from advanced plaque also contains large amounts of organic soluble carbonyls and aldehydes that are also cytotoxic. PubMed:20378845
Earlier chemical investigations of gruel from advanced lesions revealed that it contains ceroid-like insoluble material composed mainly of hydoxyapatite, iron and calcium. PubMed:20378845
Low-density lipoprotein is the major lipid involved in plaque formation. PubMed:24904418
Gruel from advanced plaque also contains large amounts of organic soluble carbonyls and aldehydes that are also cytotoxic. PubMed:20378845
Earlier chemical investigations of gruel from advanced lesions revealed that it contains ceroid-like insoluble material composed mainly of hydoxyapatite, iron and calcium. PubMed:20378845
Earlier chemical investigations of gruel from advanced lesions revealed that it contains ceroid-like insoluble material composed mainly of hydoxyapatite, iron and calcium. PubMed:20378845
Thus, it appears that these extracts oxidize ferrohemoglobin to ferrihemoglobin, thereby leading to heme instability and heme-mediated initiation of lipid peroxidation. PubMed:20378845
Expression of HO-1 provides protection against atherosclerosis in several experimental models17,18 and HO-1 deficiency in humans has been associated with the appearance of vasculature fatty streaks and atheromatous plaques at age of six.19 PubMed:20378845
Expression of HO-1 provides protection against atherosclerosis in several experimental models17,18 and HO-1 deficiency in humans has been associated with the appearance of vasculature fatty streaks and atheromatous plaques at age of six.19 PubMed:20378845
Thus, it appears that these extracts oxidize ferrohemoglobin to ferrihemoglobin, thereby leading to heme instability and heme-mediated initiation of lipid peroxidation. PubMed:20378845
Earlier chemical investigations of gruel from advanced lesions revealed that it contains ceroid-like insoluble material composed mainly of hydoxyapatite, iron and calcium. PubMed:20378845
Earlier chemical investigations of gruel from advanced lesions revealed that it contains ceroid-like insoluble material composed mainly of hydoxyapatite, iron and calcium. PubMed:20378845
Earlier chemical investigations of gruel from advanced lesions revealed that it contains ceroid-like insoluble material composed mainly of hydoxyapatite, iron and calcium. PubMed:20378845
Gruel from advanced plaque also contains large amounts of organic soluble carbonyls and aldehydes that are also cytotoxic. PubMed:20378845
Gruel from advanced plaque also contains large amounts of organic soluble carbonyls and aldehydes that are also cytotoxic. PubMed:20378845
Low-density lipoprotein is the major lipid involved in plaque formation. PubMed:24904418
BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.
If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.