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path(MESH:Reward)

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Entity

Name
Reward
Namespace
mesh
Namespace Version
20181007
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/8ccfed235e418e4c8aa576f9a5ef0f838e794c7f/external/mesh-names.belns

Appears in Networks 2

Naturally-expressed nicotinic acetylcholine receptor subtypes v1.0.0

Neuronal and Extraneuronal Nicotinic Acetylcholine Receptors. v1.0.0

In-Edges 4

a(HBP:"alpha-6-containing nAChR") association path(MESH:Reward) View Subject | View Object

a6 subunits are not widely expressed in the brain, but they are prevalent in midbrain dopaminergic (DAergic) regions associated with pleasure, reward, and mood control PubMed:21787755

Appears in Networks:
Annotations
Cell Ontology (CL)
midbrain dopaminergic neuron

p(HGNC:CHRNA6) association path(MESH:Reward) View Subject | View Object

There is an emerging consensus that nAChR a6 subunit mRNA and proteins are distributed in brain regions thought to be involved in reward and drug reinforcement, in theory being involved in DA release [135]. PubMed:21787755

Appears in Networks:
Annotations
MeSH
Brain

r(HGNC:CHRNA6) association path(MESH:Reward) View Subject | View Object

There is an emerging consensus that nAChR a6 subunit mRNA and proteins are distributed in brain regions thought to be involved in reward and drug reinforcement, in theory being involved in DA release [135]. PubMed:21787755

Appears in Networks:
Annotations
MeSH
Brain

p(MESH:"Receptors, Nicotinic") association path(MESH:Reward) View Subject | View Object

In the brain, nAChRs are widely expressed, both presyn- aptically and postsynaptically, and are involved in several functions including learning and memory, arousal, reward, motor control, and analgesia. nAChRs are also the target of nicotine, the main addictive agent delivered by cigarette smoke PubMed:28901280

Appears in Networks:

Out-Edges 4

path(MESH:Reward) association a(HBP:"alpha-6-containing nAChR") View Subject | View Object

a6 subunits are not widely expressed in the brain, but they are prevalent in midbrain dopaminergic (DAergic) regions associated with pleasure, reward, and mood control PubMed:21787755

Appears in Networks:
Annotations
Cell Ontology (CL)
midbrain dopaminergic neuron

path(MESH:Reward) association r(HGNC:CHRNA6) View Subject | View Object

There is an emerging consensus that nAChR a6 subunit mRNA and proteins are distributed in brain regions thought to be involved in reward and drug reinforcement, in theory being involved in DA release [135]. PubMed:21787755

Appears in Networks:
Annotations
MeSH
Brain

path(MESH:Reward) association p(HGNC:CHRNA6) View Subject | View Object

There is an emerging consensus that nAChR a6 subunit mRNA and proteins are distributed in brain regions thought to be involved in reward and drug reinforcement, in theory being involved in DA release [135]. PubMed:21787755

Appears in Networks:
Annotations
MeSH
Brain

path(MESH:Reward) association p(MESH:"Receptors, Nicotinic") View Subject | View Object

In the brain, nAChRs are widely expressed, both presyn- aptically and postsynaptically, and are involved in several functions including learning and memory, arousal, reward, motor control, and analgesia. nAChRs are also the target of nicotine, the main addictive agent delivered by cigarette smoke PubMed:28901280

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.