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a(MESH:"White Matter")

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Entity

Name
White Matter
Namespace
mesh
Namespace Version
20181007
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/8ccfed235e418e4c8aa576f9a5ef0f838e794c7f/external/mesh-names.belns

Appears in Networks 3

Role of the nicotinic acetylcholine receptor in Alzheimer's disease pathology and treatment v1.0.1

Nicotinic α4β2 acetylcholine receptors and cognitive function in Parkinson's disease v1.0.0

Clearance systems in the brain-implications for Alzheimer disease. v1.0.1

In-Edges 3

path(MESH:"Alzheimer Disease") negativeCorrelation a(MESH:"White Matter") View Subject | View Object

In addition, anatomical studies in AD patients showed a massive loss of brain white matter and a specific reduction of cholinergic neurons of the basal forebrain (Auld et al., 2002; Bowen et al., 1976; Coyle et al., 1983; Kim et al., 2013; Whitehouse et al., 1981, 1982) PubMed:25514383

Appears in Networks:
Annotations
MeSH
Brain

complex(HBP:"alpha-4 beta-2 nAChR") positiveCorrelation a(MESH:"White Matter") View Subject | View Object

The right cerebellar white matter revealed a sig- nificantly higher 5-I-A-85380 uptake than the left cerebellar white matter. PubMed:24762290

Appears in Networks:

path(MESH:"Alzheimer Disease") association a(MESH:"White Matter") View Subject | View Object

The gross pathological changes consist of brain atrophy, particularly in the hippocampal formation, temporal lobes and parietotemporal cortices, accompanied by cortical thinning, enlarged ventricles and white matter abnormalities, as evident on MRI. PubMed:26195256

Appears in Networks:

Out-Edges 3

a(MESH:"White Matter") negativeCorrelation path(MESH:"Alzheimer Disease") View Subject | View Object

In addition, anatomical studies in AD patients showed a massive loss of brain white matter and a specific reduction of cholinergic neurons of the basal forebrain (Auld et al., 2002; Bowen et al., 1976; Coyle et al., 1983; Kim et al., 2013; Whitehouse et al., 1981, 1982) PubMed:25514383

Appears in Networks:
Annotations
MeSH
Brain

a(MESH:"White Matter") positiveCorrelation complex(HBP:"alpha-4 beta-2 nAChR") View Subject | View Object

The right cerebellar white matter revealed a sig- nificantly higher 5-I-A-85380 uptake than the left cerebellar white matter. PubMed:24762290

Appears in Networks:

a(MESH:"White Matter") association path(MESH:"Alzheimer Disease") View Subject | View Object

The gross pathological changes consist of brain atrophy, particularly in the hippocampal formation, temporal lobes and parietotemporal cortices, accompanied by cortical thinning, enlarged ventricles and white matter abnormalities, as evident on MRI. PubMed:26195256

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.