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complex(HBP:"alpha-4 beta-2 nAChR")

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Entity

Name
alpha-4 beta-2 nAChR
Namespace
HBP
Namespace Version
None
Pattern
.*

Appears in Networks 1

Nicotinic α4β2 acetylcholine receptors and cognitive function in Parkinson's disease v1.0.0

In-Edges 9

a(MESH:"Corpus Striatum") association complex(HBP:"alpha-4 beta-2 nAChR") View Subject | View Object

The most intense accumulation of 5-I-A-85380 was detected in both thalami, pons and midbrain, and both nuclei lentiformes PubMed:24762290

Appears in Networks:

a(MESH:"Parietal Lobe") association complex(HBP:"alpha-4 beta-2 nAChR") View Subject | View Object

We found high correlation coefficients for four brain regions (right superior parietal lobule, left thalamus, right pos- terior subcortical region, and left posterior subcor- tical region) and two CERAD subtests (Word List Intrusions and Boston Naming Test), some of them were statistically significant. PubMed:24762290

Appears in Networks:

a(MESH:"White Matter") positiveCorrelation complex(HBP:"alpha-4 beta-2 nAChR") View Subject | View Object

The right cerebellar white matter revealed a sig- nificantly higher 5-I-A-85380 uptake than the left cerebellar white matter. PubMed:24762290

Appears in Networks:

a(MESH:Mesencephalon) association complex(HBP:"alpha-4 beta-2 nAChR") View Subject | View Object

The most intense accumulation of 5-I-A-85380 was detected in both thalami, pons and midbrain, and both nuclei lentiformes PubMed:24762290

Appears in Networks:

a(MESH:Pons) association complex(HBP:"alpha-4 beta-2 nAChR") View Subject | View Object

The most intense accumulation of 5-I-A-85380 was detected in both thalami, pons and midbrain, and both nuclei lentiformes PubMed:24762290

Appears in Networks:

a(MESH:Thalamus) association complex(HBP:"alpha-4 beta-2 nAChR") View Subject | View Object

The most intense accumulation of 5-I-A-85380 was detected in both thalami, pons and midbrain, and both nuclei lentiformes PubMed:24762290

Appears in Networks:

a(MESH:Thalamus) association complex(HBP:"alpha-4 beta-2 nAChR") View Subject | View Object

We found high correlation coefficients for four brain regions (right superior parietal lobule, left thalamus, right pos- terior subcortical region, and left posterior subcor- tical region) and two CERAD subtests (Word List Intrusions and Boston Naming Test), some of them were statistically significant. PubMed:24762290

Appears in Networks:

path(MESH:"Parkinson Disease") association complex(HBP:"alpha-4 beta-2 nAChR") View Subject | View Object

Furthermore, we studied in these 17 IPD patients (at Hoehn and Yahr stage 1 and 2) whether there were differences of the a4b2 nAchR densities in the brain hemisphere contralateral to the clinically more affected body side (=contralat- eral hemisphere) compared to the brain hemi- sphere ipsilateral to the clinically more affected body side (=ipsilateral hemisphere). PubMed:24762290

Appears in Networks:

path(MESH:Memory) association complex(HBP:"alpha-4 beta-2 nAChR") View Subject | View Object

We found high correlation coefficients for four brain regions (right superior parietal lobule, left thalamus, right pos- terior subcortical region, and left posterior subcor- tical region) and two CERAD subtests (Word List Intrusions and Boston Naming Test), some of them were statistically significant. PubMed:24762290

Appears in Networks:

Out-Edges 9

complex(HBP:"alpha-4 beta-2 nAChR") association a(MESH:Thalamus) View Subject | View Object

The most intense accumulation of 5-I-A-85380 was detected in both thalami, pons and midbrain, and both nuclei lentiformes PubMed:24762290

Appears in Networks:

complex(HBP:"alpha-4 beta-2 nAChR") association a(MESH:Thalamus) View Subject | View Object

We found high correlation coefficients for four brain regions (right superior parietal lobule, left thalamus, right pos- terior subcortical region, and left posterior subcor- tical region) and two CERAD subtests (Word List Intrusions and Boston Naming Test), some of them were statistically significant. PubMed:24762290

Appears in Networks:

complex(HBP:"alpha-4 beta-2 nAChR") association a(MESH:Pons) View Subject | View Object

The most intense accumulation of 5-I-A-85380 was detected in both thalami, pons and midbrain, and both nuclei lentiformes PubMed:24762290

Appears in Networks:

complex(HBP:"alpha-4 beta-2 nAChR") association a(MESH:Mesencephalon) View Subject | View Object

The most intense accumulation of 5-I-A-85380 was detected in both thalami, pons and midbrain, and both nuclei lentiformes PubMed:24762290

Appears in Networks:

complex(HBP:"alpha-4 beta-2 nAChR") association a(MESH:"Corpus Striatum") View Subject | View Object

The most intense accumulation of 5-I-A-85380 was detected in both thalami, pons and midbrain, and both nuclei lentiformes PubMed:24762290

Appears in Networks:

complex(HBP:"alpha-4 beta-2 nAChR") positiveCorrelation a(MESH:"White Matter") View Subject | View Object

The right cerebellar white matter revealed a sig- nificantly higher 5-I-A-85380 uptake than the left cerebellar white matter. PubMed:24762290

Appears in Networks:

complex(HBP:"alpha-4 beta-2 nAChR") association path(MESH:"Parkinson Disease") View Subject | View Object

Furthermore, we studied in these 17 IPD patients (at Hoehn and Yahr stage 1 and 2) whether there were differences of the a4b2 nAchR densities in the brain hemisphere contralateral to the clinically more affected body side (=contralat- eral hemisphere) compared to the brain hemi- sphere ipsilateral to the clinically more affected body side (=ipsilateral hemisphere). PubMed:24762290

Appears in Networks:

complex(HBP:"alpha-4 beta-2 nAChR") association a(MESH:"Parietal Lobe") View Subject | View Object

We found high correlation coefficients for four brain regions (right superior parietal lobule, left thalamus, right pos- terior subcortical region, and left posterior subcor- tical region) and two CERAD subtests (Word List Intrusions and Boston Naming Test), some of them were statistically significant. PubMed:24762290

Appears in Networks:

complex(HBP:"alpha-4 beta-2 nAChR") association path(MESH:Memory) View Subject | View Object

We found high correlation coefficients for four brain regions (right superior parietal lobule, left thalamus, right pos- terior subcortical region, and left posterior subcor- tical region) and two CERAD subtests (Word List Intrusions and Boston Naming Test), some of them were statistically significant. PubMed:24762290

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.