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complex(p(HBP:HBP00071), p(HGNC:NAE1))

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Components

Appears in Networks 1

Proteolytic processing of Alzeimer's beta-amyloid precursor protein v1.0.1

In-Edges 0

Out-Edges 5

complex(p(HBP:HBP00071), p(HGNC:NAE1)) hasComponent p(HBP:HBP00071) View Subject | View Object

Appears in Networks:

complex(p(HBP:HBP00071), p(HGNC:NAE1)) hasComponent p(HGNC:NAE1) View Subject | View Object

Appears in Networks:

complex(p(HBP:HBP00071), p(HGNC:NAE1)) increases bp(GO:"protein neddylation") View Subject | View Object

APP-binding protein 1 reportedly interacts with AICD and activates the neddylation pathway (Chen 2004), further down-regulating the level of beta-catenin and potentially resulting in apoptosis PubMed:22122372

Appears in Networks:
Annotations
Confidence
High
MeSH
Neurons

complex(p(HBP:HBP00071), p(HGNC:NAE1)) decreases p(HGNC:CTNNB1) View Subject | View Object

APP-binding protein 1 reportedly interacts with AICD and activates the neddylation pathway (Chen 2004), further down-regulating the level of beta-catenin and potentially resulting in apoptosis PubMed:22122372

Appears in Networks:
Annotations
Confidence
High
MeSH
Neurons

complex(p(HBP:HBP00071), p(HGNC:NAE1)) increases bp(GO:"apoptotic process") View Subject | View Object

APP-binding protein 1 reportedly interacts with AICD and activates the neddylation pathway (Chen 2004), further down-regulating the level of beta-catenin and potentially resulting in apoptosis PubMed:22122372

Appears in Networks:
Annotations
Confidence
High
MeSH
Neurons

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.