complex(p(HBP:HBP00071), p(HGNC:NAE1)) increases bp(GO:"apoptotic process")

View Subject View Object

PubMed:22122372

APP-binding protein 1 reportedly interacts with AICD and activates the neddylation pathway (Chen 2004), further down-regulating the level of beta-catenin and potentially resulting in apoptosis

Related Edges 2

• complex(p(HBP:HBP00071), p(HGNC:NAE1)) increases bp(GO:"protein neddylation")
• complex(p(HBP:HBP00071), p(HGNC:NAE1)) decreases p(HGNC:CTNNB1)

Confidence

High

MeSH

Neurons

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

---