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path(MESH:Pleasure)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
Pleasure
Namespace
mesh
Namespace Version
20181007
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/8ccfed235e418e4c8aa576f9a5ef0f838e794c7f/external/mesh-names.belns

Appears in Networks 2

Naturally-expressed nicotinic acetylcholine receptor subtypes v1.0.0

Discriminative Stimulus Properties of S(−)-Nicotine: “A Drug for All Seasons v1.0.0

In-Edges 2

a(HBP:"alpha-6-containing nAChR") association path(MESH:Pleasure) View Subject | View Object

a6 subunits are not widely expressed in the brain, but they are prevalent in midbrain dopaminergic (DAergic) regions associated with pleasure, reward, and mood control PubMed:21787755

Appears in Networks:
Annotations
Cell Ontology (CL)
midbrain dopaminergic neuron

a(CHEBI:dopamine) regulates path(MESH:Pleasure) View Subject | View Object

Moreover, (-)-nicotine (indirectly) can produce a release of dopamine in brain regions that are thought to control pleasure and motivation; dopamine is thought to underlie the pleasurable sensations experienced by smokers (e.g., [14, 15] but see [16]). PubMed:28391535

Appears in Networks:
Annotations
MeSH
Brain

Out-Edges 1

path(MESH:Pleasure) association a(HBP:"alpha-6-containing nAChR") View Subject | View Object

a6 subunits are not widely expressed in the brain, but they are prevalent in midbrain dopaminergic (DAergic) regions associated with pleasure, reward, and mood control PubMed:21787755

Appears in Networks:
Annotations
Cell Ontology (CL)
midbrain dopaminergic neuron

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.