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White Matter

Name
White Matter
Namespace Keyword
MeSHAnatomy
Namespace
MeSH
Namespace Version
20170511
Namespace URL
https://arty.scai.fraunhofer.de/artifactory/bel/annotation/mesh-anatomy/mesh-anatomy-20170511.belanno

Sample Annotated Edges 5

a(CHEBI:Anatabine) positiveCorrelation a(GO:"myelin sheath") View Subject | View Object

Interestingly, anatabine significantly prevented demyelination associated with EAE in the spinal cord (Fig. 12) PubMed:23383175

Appears in Networks:
Annotations
MeSH
Spinal Cord
MeSH
White Matter
MeSH
Encephalomyelitis

a(GO:"myelin sheath") positiveCorrelation a(CHEBI:Anatabine) View Subject | View Object

Interestingly, anatabine significantly prevented demyelination associated with EAE in the spinal cord (Fig. 12) PubMed:23383175

Appears in Networks:
Annotations
MeSH
Spinal Cord
MeSH
White Matter
MeSH
Encephalomyelitis

path(MESH:Encephalomyelitis) decreases a(GO:"myelin sheath") View Subject | View Object

Finally, Luxol Fast Blue staining showed significant myelin loss in the white matter of the spinal cord of EAE mice compared control non-immunized mice (Fig. 12) PubMed:23383175

Appears in Networks:
Annotations
MeSH
Spinal Cord
MeSH
White Matter

composite(a(CHEBI:chlorobutanol), a(PUBCHEM:9832404)) increases a(MESH:"Nerve Fibers, Myelinated") View Subject | View Object

Furthermore, FA which is used to characterize the organization of white matter fibers, was shown to be significantly increased in Adnp+/− mice, thus implying of structural impairment. Importantly, this DTI observed structural impairment was ameliorated by NA-PCB treatment (Fig. 3b). PubMed:30664622

Appears in Networks:
Annotations
MeSH
White Matter

p(HGNC:ADNP, pmod(MESH:Haploinsufficiency)) decreases a(MESH:"Nerve Fibers, Myelinated") View Subject | View Object

Furthermore, FA which is used to characterize the organization of white matter fibers, was shown to be significantly increased in Adnp+/− mice, thus implying of structural impairment. Importantly, this DTI observed structural impairment was ameliorated by NA-PCB treatment (Fig. 3b). PubMed:30664622

Appears in Networks:
Annotations
MeSH
White Matter

Showing 5 of 6 edges

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.