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  3. path(MESH:"Insulin Resistance")

path(MESH:"Insulin Resistance")

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
Insulin Resistance
Namespace
MeSH
Namespace Version
20181007
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/01c9daa61012b37dd0a1bc962521ba51a15b38f1/external/mesh-names.belns

Appears in Networks 3

albuquerque2009 v1.0.0

This file encodes the article Mammalian Nicotinic Acetylcholine Receptors: From Structure to Function by Albuquerque et al, 2009

Nuclear receptors as therapeutic targets for Alzheimer's disease. v1.0.0

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 3

path(MESH:"Tobacco Use Disorder") association path(MESH:"Insulin Resistance") View Subject | View Object

It has long been known that smokers tend to be leaner, and yet approximately four times more likely to become insulin resistant and develop type I diabetes (497), a condition that is more commonly observed in obese patients. PubMed:19126755

Appears in Networks:
Annotations
Text Location
Review

p(HGNC:PPARGC1A) association path(MESH:"Insulin Resistance") View Subject | View Object

PPAR-g is involved in lipid storage, insulin sensitivity and energy metabolism and has been shown to promote adipocyte differentiation [21]. PubMed:21718217

Appears in Networks:
Annotations
Confidence
Medium

p(MGI:Hmox1) negativeCorrelation path(MESH:"Insulin Resistance") View Subject | View Object

Furthermore, Hmox1−/− mice are susceptible to liver IR which is characterized by tissue damage in sites that are reperfused after ischemia injury and hemolysis (Devey et al., 2009). PubMed:24904418

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Liver
MeSH
Rhabdomyolysis
Text Location
Review

Out-Edges 4

path(MESH:"Insulin Resistance") association path(MESH:"Tobacco Use Disorder") View Subject | View Object

It has long been known that smokers tend to be leaner, and yet approximately four times more likely to become insulin resistant and develop type I diabetes (497), a condition that is more commonly observed in obese patients. PubMed:19126755

Appears in Networks:
Annotations
Text Location
Review

path(MESH:"Insulin Resistance") increases path(MESH:"Diabetes Mellitus, Type 1") View Subject | View Object

It has long been known that smokers tend to be leaner, and yet approximately four times more likely to become insulin resistant and develop type I diabetes (497), a condition that is more commonly observed in obese patients. PubMed:19126755

Appears in Networks:
Annotations
Text Location
Review

path(MESH:"Insulin Resistance") association p(HGNC:PPARGC1A) View Subject | View Object

PPAR-g is involved in lipid storage, insulin sensitivity and energy metabolism and has been shown to promote adipocyte differentiation [21]. PubMed:21718217

Appears in Networks:
Annotations
Confidence
Medium

path(MESH:"Insulin Resistance") negativeCorrelation p(MGI:Hmox1) View Subject | View Object

Furthermore, Hmox1−/− mice are susceptible to liver IR which is characterized by tissue damage in sites that are reperfused after ischemia injury and hemolysis (Devey et al., 2009). PubMed:24904418

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Liver
MeSH
Rhabdomyolysis
Text Location
Review

About

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.