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p(HGNC:AIM2)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
AIM2
Namespace
hgnc
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 1

Activation and regulation of the inflammasomes v1.0.0

In-Edges 4

complex(GO:"inflammasome complex") hasComponent p(HGNC:AIM2) View Subject | View Object

Appears in Networks:

a(MESH:Interferons) increases p(HGNC:AIM2) View Subject | View Object

IFNs upregulate AIM2 expression but they downregulate IL-1β expression and inhibit the NLRP3 inflammasome. PubMed:23702978

Appears in Networks:
Annotations
Confidence
High
NeuroMMSigDB
Interferon signaling subgraph
NeuroMMSigDB
Interleukin signaling subgraph

p(FPLX:IFNB) increases p(HGNC:AIM2) View Subject | View Object

In addition, AIM2 expression can be induced by IFNβ and IFNγ65,66. PubMed:23702978

Appears in Networks:
Annotations
Confidence
High
NeuroMMSigDB
Interleukin signaling subgraph

p(HGNC:IFNG) increases p(HGNC:AIM2) View Subject | View Object

In addition, AIM2 expression can be induced by IFNβ and IFNγ65,66. PubMed:23702978

Appears in Networks:
Annotations
Confidence
High
NeuroMMSigDB
Interleukin signaling subgraph

Out-Edges 0

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.