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Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

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path(MESH:Anemia) increases complex(a(MESH:Luciferases), p(MGI:Hif1a)) View Subject | View Object

D). “Right kidney  liver region” HIF/luciferase radiance increased from a baseline value of 5.30 107  1.23 107 p/s to a day 4 value of 6.72 107  1.63 107 p/s (unadjusted P  0.01, adjusted P  0.04; Fig. 7E). PubMed:29351418

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Kidney
MeSH
Liver
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path(MESH:Anemia) increases complex(a(MESH:Luciferases), p(MGI:Hif1a)) View Subject | View Object

“Gut region” HIF/luciferase radiance at the day 4 time point was 4.38 108  4.00 108 p/s, which was higher than a control value of 2.36 108  0.93 108 p/s (unadjusted P  0.001, adjusted P  0.001; Fig. 8E). PubMed:29351418

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MeSH
Kidney
MeSH
Liver
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Results

path(MESH:Anemia) increases complex(a(MESH:Luciferases), p(MGI:Hif1a)) View Subject | View Object

In addition, change in day 4 gut region HIF/luciferase radiance values from baseline in anemic mice was 1.68 108  3.48 108 p/s, which was higher than a control value of 1.08 108  1.28 108 p/s (P  0.02). PubMed:29351418

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MeSH
Kidney
MeSH
Liver
Text Location
Results

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About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.