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bp(MESH:"Platelet Adhesiveness")

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
Platelet Adhesiveness
Namespace
MeSH
Namespace Version
20181007
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/01c9daa61012b37dd0a1bc962521ba51a15b38f1/external/mesh-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 3

a(CHEBI:"iron trichloride") positiveCorrelation bp(MESH:"Platelet Adhesiveness") View Subject | View Object

Subsequent perfusion of anticoagulated whole blood through FeCl3-pretreated vessels was associated with an increase in leukocyte and platelet adhesion to the vessel wall (Fig. 1E and supplemental Video 2); however, relative to untreated aorta (Fig. 1F and supplemental Video 3) and treatment in the presence of flowing blood (Fig. 1D and supplemental Video 1), thrombus formation was not observed. PubMed:19276082

Appears in Networks:
Annotations
Cell Ontology (CL)
platelet
MeSH
Blood
Text Location
Introduction

a(MESH:Erythrocytes) increases bp(MESH:"Platelet Adhesiveness") View Subject | View Object

A remarkable rheological effect of RBCs that affects platelets in hemostasis and thrombosis is that RBCs preferentially move down the center of blood vessel, causing margination of platelets, so that they are poised to adhere preferentially to the site of vessel-wall injury [10]. PubMed:28458720

Appears in Networks:
Annotations
Text Location
Review

bp(MESH:Hematocrit) increases bp(MESH:"Platelet Adhesiveness") View Subject | View Object

The hematocrit-related blood viscosity may have physical effects on the interaction between platelets and blood vessel surfaces.Under flow conditions, platelet adhesion increases greatly with hematocrit. PubMed:28458720

Appears in Networks:
Annotations
Text Location
Review

Out-Edges 1

bp(MESH:"Platelet Adhesiveness") positiveCorrelation a(CHEBI:"iron trichloride") View Subject | View Object

Subsequent perfusion of anticoagulated whole blood through FeCl3-pretreated vessels was associated with an increase in leukocyte and platelet adhesion to the vessel wall (Fig. 1E and supplemental Video 2); however, relative to untreated aorta (Fig. 1F and supplemental Video 3) and treatment in the presence of flowing blood (Fig. 1D and supplemental Video 1), thrombus formation was not observed. PubMed:19276082

Appears in Networks:
Annotations
Cell Ontology (CL)
platelet
MeSH
Blood
Text Location
Introduction

About

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.