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path(MESH:"Mental Disorders")

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Entity

Name
Mental Disorders
Namespace
MeSH
Namespace Version
20181007
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/efc856fb009a39e4d284269a6801f79ed3d3cf56/external/mesh-names.belns

Appears in Networks 1

mTOR-Related Brain Dysfunctions in Neuropsychiatric Disorders v1.0.0

In-Edges 2

a(PUBCHEM:9832404) decreases path(MESH:"Mental Disorders") View Subject | View Object

On the other hand, chronic treatment with an eight-amino-acid peptide snippet from ADNP (NAP), also known as davunetide, restored both Beclin1 and ADNP mRNA levels along with ADNP-LC3 interaction, thus providing neuroprotection while ameliorating schizophrenic-like behavioral and cognitive deficits in Map6+/- mice PubMed:30061532

Appears in Networks:
Annotations
MeSH
Schizophrenia

complex(p(HGNC:CDK5), p(HGNC:DPYSL2)) association path(MESH:"Mental Disorders") View Subject | View Object

Remarkably, the marked reduction of p35 levels in schizophrenic brains, which mirrors enhanced CDK5 activity [247], suggests a role for CDK5-CRMP2-dependent alterations of cytoskeleton architecture and psychiatric behavior PubMed:30061532

Appears in Networks:
Annotations
MeSH
Brain

Out-Edges 1

path(MESH:"Mental Disorders") association complex(p(HGNC:CDK5), p(HGNC:DPYSL2)) View Subject | View Object

Remarkably, the marked reduction of p35 levels in schizophrenic brains, which mirrors enhanced CDK5 activity [247], suggests a role for CDK5-CRMP2-dependent alterations of cytoskeleton architecture and psychiatric behavior PubMed:30061532

Appears in Networks:
Annotations
MeSH
Brain

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BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.