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a(CHEBI:"magnesium(2+)")

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
magnesium(2+)
Namespace
chebi
Namespace Version
20180828
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/1b20f0637c395f8aa89c2e2e342d7b704062c242/external/chebi-names.belns

Appears in Networks 3

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In-Edges 2

complex(a(CHEBI:"magnesium(2+)"), p(GFAM:"Glutamate ionotropic receptor NMDA type subunits")) hasComponent a(CHEBI:"magnesium(2+)") View Subject | View Object

Appears in Networks:

composite(a(CHEBI:"magnesium(2+)"), a(CHEBI:ATP)) hasComponent a(CHEBI:"magnesium(2+)") View Subject | View Object

Appears in Networks:

Out-Edges 1

a(CHEBI:"magnesium(2+)") decreases complex(a(CHEBI:"calcium(2+)"), p(GFAM:"Glutamate ionotropic receptor NMDA type subunits")) View Subject | View Object

In individuals with normal cognitive functioning, Mg2+ blocks the passage of Ca2+ through the neuronal NMDA receptor calcium channel under resting conditions, but it is readily displaced when membrane depolarization occurs and synaptic glutamate concentrations are at peak levels (ie, when neuronal firing occurs). PubMed:16273023

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About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.