bp(MESH:"Protein Carbonylation")
A frequent oxidative modification of proteins is irreversible carbonylation which can occur by either direct oxidation where oxidants act and leave a functional carbonyl group on amino acid side chains or in the protein backbone, or, indirectly, by protein conjugation with oxidation pro- ducts of polyunsaturated fatty acids and carbohydrates [98]. PubMed:24563850
Both BSA and BSA-T attenuated heme/H2O2/NO2 −-induced protein carbonylation and lipid peroxidation. PubMed:30324533
Both BSA and BSA-T attenuated heme/H2O2/NO2 −-induced protein carbonylation and lipid peroxidation. PubMed:30324533
Heavily carbonylated proteins tend to form aggregates that are resistant to degradation and accumulate as unfolded or damaged proteins [101]. PubMed:24563850
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