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Entity

Name
mitochondrion transport along microtubule
Namespace
go
Namespace Version
20190207
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/a5b84013a08880975ca84f40999e4404b14a97e2/external/go-names.belns

Appears in Networks 1

In-Edges 12

p(HBP:"Tau C3") negativeCorrelation bp(GO:"mitochondrion transport along microtubule") View Subject | View Object

As expected, we observed a significant impairment of mitochondrial distribution with overexpression of all three tau constructs (p < 0.0001, Wilcoxon test for GFP control versus 4R-tau, GFP versus tauC3, and GFP versus K18ΔK280) (Fig. 5). PubMed:25374103

p(HBP:"Tau C3") negativeCorrelation bp(GO:"mitochondrion transport along microtubule") View Subject | View Object

Taken together, these data indicate that tau-overexpression leads to abnormal mitochondrial trafficking that can be rescued by CHIP-co-expression PubMed:25374103

p(HBP:"Tau isoform F (441 aa)") negativeCorrelation bp(GO:"mitochondrion transport along microtubule") View Subject | View Object

As expected, we observed a significant impairment of mitochondrial distribution with overexpression of all three tau constructs (p < 0.0001, Wilcoxon test for GFP control versus 4R-tau, GFP versus tauC3, and GFP versus K18ΔK280) (Fig. 5). PubMed:25374103

p(HBP:"Tau isoform F (441 aa)") negativeCorrelation bp(GO:"mitochondrion transport along microtubule") View Subject | View Object

Taken together, these data indicate that tau-overexpression leads to abnormal mitochondrial trafficking that can be rescued by CHIP-co-expression PubMed:25374103

composite(p(HBP:"4R tau", var("p.Lys280del")), p(HGNC:STUB1)) positiveCorrelation bp(GO:"mitochondrion transport along microtubule") View Subject | View Object

Taken together, these data indicate that tau-overexpression leads to abnormal mitochondrial trafficking that can be rescued by CHIP-co-expression PubMed:25374103

p(HBP:"4R tau", var("p.Lys280del")) negativeCorrelation bp(GO:"mitochondrion transport along microtubule") View Subject | View Object

As expected, we observed a significant impairment of mitochondrial distribution with overexpression of all three tau constructs (p < 0.0001, Wilcoxon test for GFP control versus 4R-tau, GFP versus tauC3, and GFP versus K18ΔK280) (Fig. 5). PubMed:25374103

p(HBP:"4R tau", var("p.Lys280del")) negativeCorrelation bp(GO:"mitochondrion transport along microtubule") View Subject | View Object

Taken together, these data indicate that tau-overexpression leads to abnormal mitochondrial trafficking that can be rescued by CHIP-co-expression PubMed:25374103

composite(p(HBP:"Tau C3"), p(HGNC:STUB1)) positiveCorrelation bp(GO:"mitochondrion transport along microtubule") View Subject | View Object

Taken together, these data indicate that tau-overexpression leads to abnormal mitochondrial trafficking that can be rescued by CHIP-co-expression PubMed:25374103

composite(p(HBP:"Tau isoform F (441 aa)"), p(HGNC:STUB1)) positiveCorrelation bp(GO:"mitochondrion transport along microtubule") View Subject | View Object

Taken together, these data indicate that tau-overexpression leads to abnormal mitochondrial trafficking that can be rescued by CHIP-co-expression PubMed:25374103

Out-Edges 12

bp(GO:"mitochondrion transport along microtubule") negativeCorrelation p(HBP:"Tau isoform F (441 aa)") View Subject | View Object

As expected, we observed a significant impairment of mitochondrial distribution with overexpression of all three tau constructs (p < 0.0001, Wilcoxon test for GFP control versus 4R-tau, GFP versus tauC3, and GFP versus K18ΔK280) (Fig. 5). PubMed:25374103

bp(GO:"mitochondrion transport along microtubule") negativeCorrelation p(HBP:"Tau isoform F (441 aa)") View Subject | View Object

Taken together, these data indicate that tau-overexpression leads to abnormal mitochondrial trafficking that can be rescued by CHIP-co-expression PubMed:25374103

bp(GO:"mitochondrion transport along microtubule") negativeCorrelation p(HBP:"Tau C3") View Subject | View Object

As expected, we observed a significant impairment of mitochondrial distribution with overexpression of all three tau constructs (p < 0.0001, Wilcoxon test for GFP control versus 4R-tau, GFP versus tauC3, and GFP versus K18ΔK280) (Fig. 5). PubMed:25374103

bp(GO:"mitochondrion transport along microtubule") negativeCorrelation p(HBP:"Tau C3") View Subject | View Object

Taken together, these data indicate that tau-overexpression leads to abnormal mitochondrial trafficking that can be rescued by CHIP-co-expression PubMed:25374103

bp(GO:"mitochondrion transport along microtubule") negativeCorrelation p(HBP:"4R tau", var("p.Lys280del")) View Subject | View Object

As expected, we observed a significant impairment of mitochondrial distribution with overexpression of all three tau constructs (p < 0.0001, Wilcoxon test for GFP control versus 4R-tau, GFP versus tauC3, and GFP versus K18ΔK280) (Fig. 5). PubMed:25374103

bp(GO:"mitochondrion transport along microtubule") negativeCorrelation p(HBP:"4R tau", var("p.Lys280del")) View Subject | View Object

Taken together, these data indicate that tau-overexpression leads to abnormal mitochondrial trafficking that can be rescued by CHIP-co-expression PubMed:25374103

bp(GO:"mitochondrion transport along microtubule") positiveCorrelation composite(p(HBP:"Tau isoform F (441 aa)"), p(HGNC:STUB1)) View Subject | View Object

Taken together, these data indicate that tau-overexpression leads to abnormal mitochondrial trafficking that can be rescued by CHIP-co-expression PubMed:25374103

bp(GO:"mitochondrion transport along microtubule") positiveCorrelation composite(p(HBP:"Tau C3"), p(HGNC:STUB1)) View Subject | View Object

Taken together, these data indicate that tau-overexpression leads to abnormal mitochondrial trafficking that can be rescued by CHIP-co-expression PubMed:25374103

bp(GO:"mitochondrion transport along microtubule") positiveCorrelation composite(p(HBP:"4R tau", var("p.Lys280del")), p(HGNC:STUB1)) View Subject | View Object

Taken together, these data indicate that tau-overexpression leads to abnormal mitochondrial trafficking that can be rescued by CHIP-co-expression PubMed:25374103

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BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.