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p(MGI:Hrg)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
Hrg
Namespace
mgi
Namespace Version
20181021
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/f2f993e599694ab5ce989cc39d789a499f75db99/external/mgi-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 0

Out-Edges 4

p(MGI:Hrg) decreases a(CHEBI:"phosphatidyl-L-serine") View Subject | View Object

Although a significant difference in PS expressionwas not observed among the CLP groups treated with PBS, HSA or HRG, incubation of erythrocytes for 4 h enabled the observation of beneficial effects of HRG on PS expression on erythrocytes (Fig. 5B). PubMed:29544683

Appears in Networks:
Annotations
MeSH
Erythrocyte Membrane
MeSH
Sepsis
Text Location
Results

p(MGI:Hrg) decreases path(MESH:Hemolysis) View Subject | View Object

Hemin-induced hemolysis was also inhibited by HRG and HRGderived peptide (amino acid sequence in the Histidine-rich domain of HRG: HHPHGHHPHG) (Fig. 6A and B). PubMed:29544683

Appears in Networks:
Annotations
MeSH
Erythrocyte Membrane
MeSH
Sepsis
Text Location
Results

p(MGI:Hrg) decreases a(HM:Immunothrombosis) View Subject | View Object

Supplementary treatment of septic mice with purified HRG from human plasma remarkably suppressed immunothrombosis in the lungs as well as the associated inflammation. PubMed:29544683

Appears in Networks:
Annotations
MeSH
Lung
MeSH
Sepsis
Text Location
Discussion

p(MGI:Hrg) decreases path(MESH:Inflammation) View Subject | View Object

Supplementary treatment of septic mice with purified HRG from human plasma remarkably suppressed immunothrombosis in the lungs as well as the associated inflammation. PubMed:29544683

Appears in Networks:
Annotations
MeSH
Lung
MeSH
Sepsis
Text Location
Discussion

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.