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a(CHEBI:"adenosine triphosphate")

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Entity

Name
adenosine triphosphate
Namespace
chebi
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/chebi-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 4

a(CHEBI:heme) decreases a(CHEBI:"adenosine triphosphate") View Subject | View Object

In serum-free conditions, NaOH-dissolved heme (final pH 7.8) reduced cellular ATP in both cell types in a dose-dependent manner after 8 hours of exposure (Figure 2A) PubMed:29610666

Appears in Networks:
Annotations
Cell Ontology (CL)
neutrophil
MeSH
Human Umbilical Vein Endothelial Cells
Text Location
Results

a(CHEBI:methemoglobin) causesNoChange a(CHEBI:"adenosine triphosphate") View Subject | View Object

In contrast, less ATP depletion was observed during exposure to heme-albumin, and no effect could be detected when either cell type was exposed to metHb or oxyHb at concentrations of up to 500 lmolL1, even in the absence of serum. PubMed:29610666

Appears in Networks:
Annotations
Cell Ontology (CL)
neutrophil
MeSH
Human Umbilical Vein Endothelial Cells
Text Location
Results

a(CHEBI:oxyhemoglobin) causesNoChange a(CHEBI:"adenosine triphosphate") View Subject | View Object

In contrast, less ATP depletion was observed during exposure to heme-albumin, and no effect could be detected when either cell type was exposed to metHb or oxyHb at concentrations of up to 500 lmolL1, even in the absence of serum. PubMed:29610666

Appears in Networks:
Annotations
Cell Ontology (CL)
neutrophil
MeSH
Human Umbilical Vein Endothelial Cells
Text Location
Results

complex(a(CHEBI:heme), p(HGNC:ALB)) positiveCorrelation a(CHEBI:"adenosine triphosphate") View Subject | View Object

In contrast, less ATP depletion was observed during exposure to heme-albumin, and no effect could be detected when either cell type was exposed to metHb or oxyHb at concentrations of up to 500 lmolL1, even in the absence of serum. PubMed:29610666

Appears in Networks:
Annotations
Cell Ontology (CL)
neutrophil
MeSH
Human Umbilical Vein Endothelial Cells
Text Location
Results

Out-Edges 1

a(CHEBI:"adenosine triphosphate") positiveCorrelation complex(a(CHEBI:heme), p(HGNC:ALB)) View Subject | View Object

In contrast, less ATP depletion was observed during exposure to heme-albumin, and no effect could be detected when either cell type was exposed to metHb or oxyHb at concentrations of up to 500 lmolL1, even in the absence of serum. PubMed:29610666

Appears in Networks:
Annotations
Cell Ontology (CL)
neutrophil
MeSH
Human Umbilical Vein Endothelial Cells
Text Location
Results

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.