1. Catalog
  2. Namespaces
  3. NeuroMMSigDB
  4. Cyclin-CDK subgraph

Cyclin-CDK subgraph

Name
Cyclin-CDK subgraph
Namespace Keyword
Subgraph
Namespace
NeuroMMSigDB
Namespace Version
1.0.3
Namespace URL
https://arty.scai.fraunhofer.de/artifactory/bel/annotation/neurommsig/neurommsig-1.0.3.belanno

Sample Annotated Edges 5

p(HGNC:IL18) increases p(HGNC:CDK5) View Subject | View Object

Pro-inflammatory IL-18 increases AD-associated A beta deposition in human neuron-like cells in culture [55]. IL-18 also increases the expression of glycogen synthase kinase 3 beta (GSK-3 beta ) and cyclin-dependent kinase 5, both of which are involved in hyperphos- phorylation of the tau protein [56]. PubMed:27314526

Appears in Networks:
Annotations
Confidence
High
MeSH
Alzheimer Disease
NeuroMMSigDB
Amyloidogenic subgraph
NeuroMMSigDB
Cyclin-CDK subgraph
NeuroMMSigDB
GSK3 subgraph
NeuroMMSigDB
Interleukin signaling subgraph
NeuroMMSigDB
Tau protein subgraph

p(HGNC:GSK3B) increases p(HGNC:MAPT, pmod(Ph)) View Subject | View Object

Pro-inflammatory IL-18 increases AD-associated A beta deposition in human neuron-like cells in culture [55]. IL-18 also increases the expression of glycogen synthase kinase 3 beta (GSK-3 beta ) and cyclin-dependent kinase 5, both of which are involved in hyperphos- phorylation of the tau protein [56]. PubMed:27314526

Appears in Networks:
Annotations
Confidence
High
MeSH
Alzheimer Disease
NeuroMMSigDB
Amyloidogenic subgraph
NeuroMMSigDB
Cyclin-CDK subgraph
NeuroMMSigDB
GSK3 subgraph
NeuroMMSigDB
Interleukin signaling subgraph
NeuroMMSigDB
Tau protein subgraph

p(HGNC:CDK5) increases p(HGNC:MAPT, pmod(Ph)) View Subject | View Object

Pro-inflammatory IL-18 increases AD-associated A beta deposition in human neuron-like cells in culture [55]. IL-18 also increases the expression of glycogen synthase kinase 3 beta (GSK-3 beta ) and cyclin-dependent kinase 5, both of which are involved in hyperphos- phorylation of the tau protein [56]. PubMed:27314526

Appears in Networks:
Annotations
Confidence
High
MeSH
Alzheimer Disease
NeuroMMSigDB
Amyloidogenic subgraph
NeuroMMSigDB
Cyclin-CDK subgraph
NeuroMMSigDB
GSK3 subgraph
NeuroMMSigDB
Interleukin signaling subgraph
NeuroMMSigDB
Tau protein subgraph

p(HGNC:IL18) increases p(HGNC:GSK3B) View Subject | View Object

Pro-inflammatory IL-18 increases AD-associated A beta deposition in human neuron-like cells in culture [55]. IL-18 also increases the expression of glycogen synthase kinase 3 beta (GSK-3 beta ) and cyclin-dependent kinase 5, both of which are involved in hyperphos- phorylation of the tau protein [56]. PubMed:27314526

Appears in Networks:
Annotations
Confidence
High
MeSH
Alzheimer Disease
NeuroMMSigDB
Amyloidogenic subgraph
NeuroMMSigDB
Cyclin-CDK subgraph
NeuroMMSigDB
GSK3 subgraph
NeuroMMSigDB
Interleukin signaling subgraph
NeuroMMSigDB
Tau protein subgraph

p(HGNC:IL18) increases a(CHEBI:"amyloid-beta") View Subject | View Object

Pro-inflammatory IL-18 increases AD-associated A beta deposition in human neuron-like cells in culture [55]. IL-18 also increases the expression of glycogen synthase kinase 3 beta (GSK-3 beta ) and cyclin-dependent kinase 5, both of which are involved in hyperphos- phorylation of the tau protein [56]. PubMed:27314526

Appears in Networks:
Annotations
Confidence
High
MeSH
Neurons
MeSH
Alzheimer Disease
NeuroMMSigDB
Amyloidogenic subgraph
NeuroMMSigDB
Cyclin-CDK subgraph
NeuroMMSigDB
GSK3 subgraph
NeuroMMSigDB
Interleukin signaling subgraph
NeuroMMSigDB
Tau protein subgraph

Showing 5 of 5 edges

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.