1. Catalog
  2. Namespaces
  3. MeSH
  4. Hemolysis

Hemolysis

Name
Hemolysis
Namespace Keyword
MeSHDisease
Namespace
MeSH
Namespace Version
20170511
Namespace URL
https://arty.scai.fraunhofer.de/artifactory/bel/annotation/mesh-diseases/mesh-diseases-20170511.belanno

Sample Annotated Edges 5

a(MESH:"Complement Membrane Attack Complex") increases path(MESH:Hemolysis) View Subject | View Object

Ultimately, activation of the complement cascade results in formation of the terminal complement complex C5b-9, the so-called membrane attack complex, and consequently a pore formation resulting in osmotic lysis of the target [71]. In the case of red blood cells, hemolysis will result. PubMed:29956069

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Liver
MeSH
Hemolysis
Text Location
Review

a(MESH:"Complement Membrane Attack Complex") increases bp(GO:cytolysis) View Subject | View Object

Ultimately, activation of the complement cascade results in formation of the terminal complement complex C5b-9, the so-called membrane attack complex, and consequently a pore formation resulting in osmotic lysis of the target [71]. In the case of red blood cells, hemolysis will result. PubMed:29956069

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Liver
MeSH
Hemolysis
Text Location
Review

a(MESH:"Lymph Nodes") increases deg(complex(GO:"IgG immunoglobulin complex")) View Subject | View Object

During extravascular hemolysis, the IgG-coated red blood cells are degraded in the so-called reticuloendothelial systems such as liver, spleen, and lymph nodes. PubMed:29956069

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Liver
MeSH
Hemolysis
Text Location
Review

a(MESH:Liver) increases deg(complex(GO:"IgG immunoglobulin complex")) View Subject | View Object

During extravascular hemolysis, the IgG-coated red blood cells are degraded in the so-called reticuloendothelial systems such as liver, spleen, and lymph nodes. PubMed:29956069

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Liver
MeSH
Hemolysis
Text Location
Review

a(MESH:Spleen) increases deg(complex(GO:"IgG immunoglobulin complex")) View Subject | View Object

During extravascular hemolysis, the IgG-coated red blood cells are degraded in the so-called reticuloendothelial systems such as liver, spleen, and lymph nodes. PubMed:29956069

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Liver
MeSH
Hemolysis
Text Location
Review

Showing 5 of 5 edges

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.