a(MESH:Microglia) increases p(HGNC:P2RX7)

View Subject View Object

PubMed:27314526

P2X7 expressed by microglial cells will also activate the NLP3 inflammasome [30, 32] and the expression of P2X7 is likely to be increased in AD brains [35].

Related Edges 3

• p(HGNC:P2RX7) increases act(complex(GO:"NLRP3 inflammasome complex"))
• p(HGNC:P2RX7) positiveCorrelation path(MESH:"Alzheimer Disease")
• path(MESH:"Alzheimer Disease") positiveCorrelation p(HGNC:P2RX7)

Confidence

Medium

MeSH

Alzheimer Disease

NeuroMMSigDB

Caspase subgraph

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

---