1. Catalog
  2. Nodes
  3. bp(GO:"leukocyte adhesion to vascular endothelial cell")

bp(GO:"leukocyte adhesion to vascular endothelial cell")

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
leukocyte adhesion to vascular endothelial cell
Namespace
go
Namespace Version
20180921
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/go-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 2

a(CHEBI:"iron trichloride") positiveCorrelation bp(GO:"leukocyte adhesion to vascular endothelial cell") View Subject | View Object

Subsequent perfusion of anticoagulated whole blood through FeCl3-pretreated vessels was associated with an increase in leukocyte and platelet adhesion to the vessel wall (Fig. 1E and supplemental Video 2); however, relative to untreated aorta (Fig. 1F and supplemental Video 3) and treatment in the presence of flowing blood (Fig. 1D and supplemental Video 1), thrombus formation was not observed. PubMed:19276082

Appears in Networks:
Annotations
Cell Ontology (CL)
platelet
MeSH
Blood
Text Location
Introduction

a(CHEBI:heme) positiveCorrelation bp(GO:"leukocyte adhesion to vascular endothelial cell") View Subject | View Object

As a consequence, infused heme (hemin) has been demonstrated to enhance leukocyte adhesion to the vessel wall (17, 18), a finding confirmed in the current study. PubMed:19276082

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Aorta
Text Location
Discussion

Out-Edges 2

bp(GO:"leukocyte adhesion to vascular endothelial cell") positiveCorrelation a(CHEBI:"iron trichloride") View Subject | View Object

Subsequent perfusion of anticoagulated whole blood through FeCl3-pretreated vessels was associated with an increase in leukocyte and platelet adhesion to the vessel wall (Fig. 1E and supplemental Video 2); however, relative to untreated aorta (Fig. 1F and supplemental Video 3) and treatment in the presence of flowing blood (Fig. 1D and supplemental Video 1), thrombus formation was not observed. PubMed:19276082

Appears in Networks:
Annotations
Cell Ontology (CL)
platelet
MeSH
Blood
Text Location
Introduction

bp(GO:"leukocyte adhesion to vascular endothelial cell") positiveCorrelation a(CHEBI:heme) View Subject | View Object

As a consequence, infused heme (hemin) has been demonstrated to enhance leukocyte adhesion to the vessel wall (17, 18), a finding confirmed in the current study. PubMed:19276082

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Aorta
Text Location
Discussion

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.