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bp(HM:erythrophagocytosis)

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Entity

Name
erythrophagocytosis
Namespace
HM
Namespace Version
None
Pattern
.*

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 3

bp(HM:"heme-iron recycling") positiveCorrelation bp(HM:erythrophagocytosis) View Subject | View Object

When RBCs become senescent or the number of damaged RBCs increases in the circulation, macrophages from the reticuloendothelial system (RES, spleen and liver) contribute to RBC clearance and subsequently promote heme-iron recycling through erythrophagocytosis (EP). PubMed:30248094

Appears in Networks:
Annotations
Text Location
Introduction

p(MGI:Slc48a1) positiveCorrelation bp(HM:erythrophagocytosis) View Subject | View Object

HRG1 mRNA is upregulated during erythrophagocytosis (EP) in mouse bone marrow derived macrophages (BMDMs) and HRG1 protein is strongly expressed in macrophages of the reticuloendothelial system (RES) and specifically localizes to the phagolysosomal membranes [11]. PubMed:30248094

Appears in Networks:
Annotations
Cell Ontology (CL)
macrophage
MeSH
Cytoplasm
Text Location
Introduction

r(MGI:Slc48a1) positiveCorrelation bp(HM:erythrophagocytosis) View Subject | View Object

HRG1 mRNA is upregulated during erythrophagocytosis (EP) in mouse bone marrow derived macrophages (BMDMs) and HRG1 protein is strongly expressed in macrophages of the reticuloendothelial system (RES) and specifically localizes to the phagolysosomal membranes [11]. PubMed:30248094

Appears in Networks:
Annotations
Cell Ontology (CL)
macrophage
MeSH
Cytoplasm
Text Location
Introduction

Out-Edges 3

bp(HM:erythrophagocytosis) positiveCorrelation bp(HM:"heme-iron recycling") View Subject | View Object

When RBCs become senescent or the number of damaged RBCs increases in the circulation, macrophages from the reticuloendothelial system (RES, spleen and liver) contribute to RBC clearance and subsequently promote heme-iron recycling through erythrophagocytosis (EP). PubMed:30248094

Appears in Networks:
Annotations
Text Location
Introduction

bp(HM:erythrophagocytosis) positiveCorrelation r(MGI:Slc48a1) View Subject | View Object

HRG1 mRNA is upregulated during erythrophagocytosis (EP) in mouse bone marrow derived macrophages (BMDMs) and HRG1 protein is strongly expressed in macrophages of the reticuloendothelial system (RES) and specifically localizes to the phagolysosomal membranes [11]. PubMed:30248094

Appears in Networks:
Annotations
Cell Ontology (CL)
macrophage
MeSH
Cytoplasm
Text Location
Introduction

bp(HM:erythrophagocytosis) positiveCorrelation p(MGI:Slc48a1) View Subject | View Object

HRG1 mRNA is upregulated during erythrophagocytosis (EP) in mouse bone marrow derived macrophages (BMDMs) and HRG1 protein is strongly expressed in macrophages of the reticuloendothelial system (RES) and specifically localizes to the phagolysosomal membranes [11]. PubMed:30248094

Appears in Networks:
Annotations
Cell Ontology (CL)
macrophage
MeSH
Cytoplasm
Text Location
Introduction

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.