1. Catalog
  2. Nodes
  3. complex(p(HGNC:PPP2R1A), p(INTERPRO:"Protein phosphatase 2A, regulatory B subunit, B56"))

complex(p(HGNC:PPP2R1A), p(INTERPRO:"Protein phosphatase 2A, regulatory B subunit, B56"))

Appears in Networks 1

Assembly and structure of protein phosphatase 2A v1.0.0

In-Edges 2

act(p(HGNC:PPP2R1A)) increases complex(p(HGNC:PPP2R1A), p(INTERPRO:"Protein phosphatase 2A, regulatory B subunit, B56")) View Subject | View Object

First, conformational flexibility of the scaffold subunit is required for binding to the catalytic subunit and possibly other interacting proteins such as the regulatory subunits. PubMed:19277525

Appears in Networks:

p(INTERPRO:"Protein phosphatase 2A, regulatory B subunit, B56") regulates complex(p(HGNC:PPP2R1A), p(INTERPRO:"Protein phosphatase 2A, regulatory B subunit, B56")) View Subject | View Object

For example, two regions of the B′ subunit were found to mediate interaction with the scaffold subunit of PP2A PubMed:19277525

Appears in Networks:

Out-Edges 2

complex(p(HGNC:PPP2R1A), p(INTERPRO:"Protein phosphatase 2A, regulatory B subunit, B56")) hasComponent p(INTERPRO:"Protein phosphatase 2A, regulatory B subunit, B56") View Subject | View Object

Appears in Networks:

complex(p(HGNC:PPP2R1A), p(INTERPRO:"Protein phosphatase 2A, regulatory B subunit, B56")) hasComponent p(HGNC:PPP2R1A) View Subject | View Object

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.