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path(MESH:"Brain Edema")

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
Brain Edema
Namespace
MeSH
Namespace Version
20181007
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/01c9daa61012b37dd0a1bc962521ba51a15b38f1/external/mesh-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 3

a(CHEBI:"desferrioxamine B") negativeCorrelation path(MESH:"Brain Edema") View Subject | View Object

There was a tendency that lysed RBC-induced brain edema was less in deferoxamine-treated group (brain water content in the ipsilateral hemisphere: 79.8±0.6% vs. 80.5±0.7% in the saline coinjection group, n¼6, P40.05). PubMed:24667910

Appears in Networks:
Annotations
MeSH
Ependyma
Text Location
Results

p(HGNC:TLR4) positiveCorrelation path(MESH:"Brain Edema") View Subject | View Object

In fact, Tlr4-/- or anti-TLR4 treatment suppresses heme-induced neuroinflammation, edema, and neurologic deficit. PubMed:24904418

Appears in Networks:
Annotations
Cell Ontology (CL)
macrophage
MeSH
Liver
MeSH
Cerebral Hemorrhage
Text Location
Review

p(HGNC:NLRP3) positiveCorrelation path(MESH:"Brain Edema") View Subject | View Object

. Interestingly, NLRP3 knockdown and mROS inhibitors reduce brain edema and improve neurological functions (Ma et al., 2014). PubMed:24904418

Appears in Networks:
Annotations
Cell Ontology (CL)
macrophage
MeSH
Liver
MeSH
Cerebral Hemorrhage
Text Location
Review

Out-Edges 3

path(MESH:"Brain Edema") positiveCorrelation p(HGNC:NLRP3) View Subject | View Object

. Interestingly, NLRP3 knockdown and mROS inhibitors reduce brain edema and improve neurological functions (Ma et al., 2014). PubMed:24904418

Appears in Networks:
Annotations
Cell Ontology (CL)
macrophage
MeSH
Liver
MeSH
Cerebral Hemorrhage
Text Location
Review

path(MESH:"Brain Edema") negativeCorrelation a(CHEBI:"desferrioxamine B") View Subject | View Object

There was a tendency that lysed RBC-induced brain edema was less in deferoxamine-treated group (brain water content in the ipsilateral hemisphere: 79.8±0.6% vs. 80.5±0.7% in the saline coinjection group, n¼6, P40.05). PubMed:24667910

Appears in Networks:
Annotations
MeSH
Ependyma
Text Location
Results

path(MESH:"Brain Edema") positiveCorrelation p(HGNC:TLR4) View Subject | View Object

In fact, Tlr4-/- or anti-TLR4 treatment suppresses heme-induced neuroinflammation, edema, and neurologic deficit. PubMed:24904418

Appears in Networks:
Annotations
Cell Ontology (CL)
macrophage
MeSH
Liver
MeSH
Cerebral Hemorrhage
Text Location
Review

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.