p(HGNC:PPP2R2A)
In neurons, B55 α and B55 β are localized in the cytoplasm, whereas B55 γ is localized in the cytoskeletal fraction. PubMed:23454242
In mammals, B55 is associated with cytoskeletal dynamics and nuclear translocation. PubMed:23454242
Within the brain, ACB55 (B55) is the major PP2A B iso- form and it binds to tau with high affinity both in in vitro protein-protein interaction paradigms and in cell cultures [36, 37]. PubMed:22299660
Analyses of protein expression by using gel electrophore- sis and western blotting have shown not only a reduction of PP2A C expression levels but also a marked reduction of B55, thus indicating that PP2A impairment is the result of combined effects of different subunits [60]. PubMed:22299660
In mammals, B55 is associated with cytoskeletal dynamics and nuclear translocation. PubMed:23454242
In neurons, B55 α and B55 β are localized in the cytoplasm, whereas B55 γ is localized in the cytoskeletal fraction. PubMed:23454242
It has been shown in yeast that CDC55 (B55 in human) is essential for cytokinesis. PubMed:23454242
Within the brain, ACB55 (B55) is the major PP2A B iso- form and it binds to tau with high affinity both in in vitro protein-protein interaction paradigms and in cell cultures [36, 37]. PubMed:22299660
Analyses of protein expression by using gel electrophore- sis and western blotting have shown not only a reduction of PP2A C expression levels but also a marked reduction of B55, thus indicating that PP2A impairment is the result of combined effects of different subunits [60]. PubMed:22299660
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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.