complex(GO:"kinesin complex")

Entity

Name

kinesin complex

Namespace

go

Namespace Version

20180921

Namespace URL

https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/go-names.belns

TAU Interactions Section of NESTOR

These include the scaffold protein JNK interacting protein (JIP) that is involved in the linkage of cargos to the kinesin-I motor complex via KLC (25, 28–33).This complex is formed by the kinesin heavy chain (KIF5; previously termed KHC), which interacts with microtubules, and kinesin light chain (KLC), which mediates cargo linkage. In addition, scaffolding proteins are involved such as the JIP1 that binds to KLC (21). PubMed:19491104

These include the scaffold protein JNK interacting protein (JIP) that is involved in the linkage of cargos to the kinesin-I motor complex via KLC (25, 28–33).This complex is formed by the kinesin heavy chain (KIF5; previously termed KHC), which interacts with microtubules, and kinesin light chain (KLC), which mediates cargo linkage. In addition, scaffolding proteins are involved such as the JIP1 that binds to KLC (21). PubMed:19491104

These include the scaffold protein JNK interacting protein (JIP) that is involved in the linkage of cargos to the kinesin-I motor complex via KLC (25, 28–33).This complex is formed by the kinesin heavy chain (KIF5; previously termed KHC), which interacts with microtubules, and kinesin light chain (KLC), which mediates cargo linkage. In addition, scaffolding proteins are involved such as the JIP1 that binds to KLC (21). PubMed:19491104

For instance, hyperphosphorylated tau can interact with JIP1 and thus impair the formation of kinesin complex PubMed:26631930

For example, hyperphosphorylated tau but not unphosphorylated tau can interact with the kinesin-associated protein JUN N‑terminal kinase-interacting protein 1 (JIP1) and thus impair the formation of the kinesin complex,which mediates axonal transport PubMed:26631930

These include the scaffold protein JNK interacting protein (JIP) that is involved in the linkage of cargos to the kinesin-I motor complex via KLC (25, 28–33).This complex is formed by the kinesin heavy chain (KIF5; previously termed KHC), which interacts with microtubules, and kinesin light chain (KLC), which mediates cargo linkage. In addition, scaffolding proteins are involved such as the JIP1 that binds to KLC (21). PubMed:19491104

These include the scaffold protein JNK interacting protein (JIP) that is involved in the linkage of cargos to the kinesin-I motor complex via KLC (25, 28–33).This complex is formed by the kinesin heavy chain (KIF5; previously termed KHC), which interacts with microtubules, and kinesin light chain (KLC), which mediates cargo linkage. In addition, scaffolding proteins are involved such as the JIP1 that binds to KLC (21). PubMed:19491104

These include the scaffold protein JNK interacting protein (JIP) that is involved in the linkage of cargos to the kinesin-I motor complex via KLC (25, 28–33).This complex is formed by the kinesin heavy chain (KIF5; previously termed KHC), which interacts with microtubules, and kinesin light chain (KLC), which mediates cargo linkage. In addition, scaffolding proteins are involved such as the JIP1 that binds to KLC (21). PubMed:19491104

For example, hyperphosphorylated tau but not unphosphorylated tau can interact with the kinesin-associated protein JUN N‑terminal kinase-interacting protein 1 (JIP1) and thus impair the formation of the kinesin complex,which mediates axonal transport PubMed:26631930