bp(GO:"vesicle-mediated transport") positiveCorrelation act(complex(GO:"kinesin complex"))

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PubMed:19491104

These include the scaffold protein JNK interacting protein (JIP) that is involved in the linkage of cargos to the kinesin-I motor complex via KLC (25, 28–33).This complex is formed by the kinesin heavy chain (KIF5; previously termed KHC), which interacts with microtubules, and kinesin light chain (KLC), which mediates cargo linkage. In addition, scaffolding proteins are involved such as the JIP1 that binds to KLC (21).

Related Edges 9

• act(complex(GO:"kinesin complex")) positiveCorrelation act(p(HGNC:MAPK8IP1))
• act(complex(GO:"kinesin complex")) positiveCorrelation act(p(HGNC:KLC1))
• act(complex(GO:"kinesin complex")) positiveCorrelation bp(GO:"vesicle-mediated transport")
• complex(GO:microtubule) association p(HGNC:KIF5B)
• p(HGNC:KIF5B) association complex(GO:microtubule)
• act(p(HGNC:KLC1)) positiveCorrelation act(complex(GO:"kinesin complex"))
• p(HGNC:KLC1) association p(HGNC:MAPK8IP1)
• act(p(HGNC:MAPK8IP1)) positiveCorrelation act(complex(GO:"kinesin complex"))
• p(HGNC:MAPK8IP1) association p(HGNC:KLC1)

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