a(MESH:Axons)

Entity

Name

Axons

Namespace

mesh

Namespace Version

20181007

Namespace URL

https://raw.githubusercontent.com/pharmacome/terminology/8ccfed235e418e4c8aa576f9a5ef0f838e794c7f/external/mesh-names.belns

The axonal density of mitochondria, which is slightly lower in proaggregant compared with antiaggregant Tau transgenic slices, is marginally decreased by 64627 treatment albeit in a genotype-independent manner (Fig. S7) PubMed:27671637

The axonal density of mitochondria, which is slightly lower in proaggregant compared with antiaggregant Tau transgenic slices, is marginally decreased by 64627 treatment albeit in a genotype-independent manner (Fig. S7) PubMed:27671637

The axons of transfected neurons (Fig. 1 G and I) clearly reveal small inclusions of Tau (∼1 μm in size, arrowheads), although presynaptic boutons (e.g., giant mossy fiber boutons) are only marginally stained for Tau (Fig. 1I and Fig. S2 A and B; arrow), indicating that Tau does not accumulate at presynaptic boutons in these slices PubMed:27671637

The axonal density of mitochondria, which is slightly lower in proaggregant compared with antiaggregant Tau transgenic slices, is marginally decreased by 64627 treatment albeit in a genotype-independent manner (Fig. S7) PubMed:27671637

. In ALS, accumulation of NFs is a prominent feature (Rouleau et al., 1996), and it has been demonstrated that NFs contribute heavily to the axonopathy of tau transgenic mice (Ishihara et al., 2001a). PubMed:12428809

Surprisingly, the axonopathy was rescued in the tau x GSK-3β double-transgenic mice, together with a near-total normalization of the functional disabilities. PubMed:12428809

The axons of transfected neurons (Fig. 1 G and I) clearly reveal small inclusions of Tau (∼1 μm in size, arrowheads), although presynaptic boutons (e.g., giant mossy fiber boutons) are only marginally stained for Tau (Fig. 1I and Fig. S2 A and B; arrow), indicating that Tau does not accumulate at presynaptic boutons in these slices PubMed:27671637

. In ALS, accumulation of NFs is a prominent feature (Rouleau et al., 1996), and it has been demonstrated that NFs contribute heavily to the axonopathy of tau transgenic mice (Ishihara et al., 2001a). PubMed:12428809