1. Catalog
  2. Nodes
  3. complex(p(HGNC:PPP2CB), p(HGNC:PPP2R1A))

complex(p(HGNC:PPP2CB), p(HGNC:PPP2R1A))

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Components

Appears in Networks 1

Protein phosphatase 2A dysfunction in Alzheimer’s disease v1.0.0

In-Edges 1

p(HGNC:PPP2R1B, pmod(Ph, Ser), pmod(Ph, Thr)) decreases complex(p(HGNC:PPP2CB), p(HGNC:PPP2R1A)) View Subject | View Object

A recent report also indicates the existence of regulated phosphorylation of the scaffolding A subunit on Ser/Thr residues, which affects its binding to the catalytic subunit and PP2A signaling in the heart (Kotlo et al.,2014). PubMed:24653673

Appears in Networks:
Annotations
MeSH
Heart

Out-Edges 2

complex(p(HGNC:PPP2CB), p(HGNC:PPP2R1A)) hasComponent p(HGNC:PPP2CB) View Subject | View Object

Appears in Networks:

complex(p(HGNC:PPP2CB), p(HGNC:PPP2R1A)) hasComponent p(HGNC:PPP2R1A) View Subject | View Object

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.