1. Catalog
  2. Nodes
  3. a(MESH:"Cerebrospinal Fluid")

a(MESH:"Cerebrospinal Fluid")

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
Cerebrospinal Fluid
Namespace
mesh
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/mesh-names.belns

Appears in Networks 2

Clearance systems in the brain-implications for Alzheimer disease. v1.0.1

Clearance of Amyloid Beta and Tau in Alzheimer’s Disease:from Mechanisms to Therapy v1.0.1

In-Edges 3

path(MESH:Aging) decreases a(MESH:"Cerebrospinal Fluid") View Subject | View Object

First, in ageing, and particularly in AD, CSF production by the choroid plexus is reduced, as shown by decreased water secretion into the ventricles via AQP1 water channels. PubMed:26195256

Appears in Networks:
Annotations
MeSH
Hippocampus
MeSH
Temporal Lobe

a(CHEBI:"amyloid-beta") decreases a(MESH:"Cerebrospinal Fluid") View Subject | View Object

In addition, Aβ deposition in CP also blocks CSF production in AD (Serot et al. 2012). PubMed:29626319

Appears in Networks:
Annotations
MeSH
Alzheimer Disease

a(MESH:"Choroid Plexus") increases a(MESH:"Cerebrospinal Fluid") View Subject | View Object

CSF is produced mainly by choroid plexus PubMed:29626319

Appears in Networks:

Out-Edges 0

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.