1. Catalog
  2. Nodes
  3. a(CHEBI:pentosidine)

a(CHEBI:pentosidine)

Equivalencies: 0 | Classes: 1 | Children: 0 | Explore

Entity

Name
pentosidine
Namespace
chebi
Namespace Version
20190224
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/c328ad964c08967a0417a887510b97b965a62fa5/external/chebi-names.belns

Appears in Networks 1

Upstream regulators and downstream effectors of NF-κBinAlzheimer's disease v1.0.0

In-Edges 2

complex(a(CHEBI:pentosidine), p(HGNC:AGER)) hasComponent a(CHEBI:pentosidine) View Subject | View Object

Appears in Networks:

path(MESH:"Alzheimer Disease") positiveCorrelation a(CHEBI:pentosidine) View Subject | View Object

Two AGEs, such as pentosidine and glyceraldehyde derived pyridinium (GLAP), both found increased in AD brains, were able to upregulate BACE1 through their binding with RAGE and consequent activation of NF-κB, providing a pathologic link between diabetes and AD [49]. PubMed:27288790

Appears in Networks:
Annotations
MeSH
Brain

Out-Edges 2

a(CHEBI:pentosidine) isA a(CHEBI:"advanced glycation end-product") View Subject | View Object

Appears in Networks:

a(CHEBI:pentosidine) positiveCorrelation path(MESH:"Alzheimer Disease") View Subject | View Object

Two AGEs, such as pentosidine and glyceraldehyde derived pyridinium (GLAP), both found increased in AD brains, were able to upregulate BACE1 through their binding with RAGE and consequent activation of NF-κB, providing a pathologic link between diabetes and AD [49]. PubMed:27288790

Appears in Networks:
Annotations
MeSH
Brain

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.